Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report
<i>Background</i>: Acute mesenteric ischemia (AMI) is a life-threatening condition, and in 50% of patients, AMI is caused by acute superior mesenteric artery (SMA) embolism. Endovascular treatment is increasingly being considered the primary modality in selected cases. Many studies have...
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MDPI AG
2023-10-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/11/1889 |
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| author | Yang-Won Kim Ho-Cheol Choi Won-Jeong Yang Byeong-Ju Koo Jae-Kyeong Ahn Jeong-Pyo Lee Jae-Bum Na Sa-Hong Jo Sung-Eun Park Jung-Ho Won |
| author_facet | Yang-Won Kim Ho-Cheol Choi Won-Jeong Yang Byeong-Ju Koo Jae-Kyeong Ahn Jeong-Pyo Lee Jae-Bum Na Sa-Hong Jo Sung-Eun Park Jung-Ho Won |
| author_sort | Yang-Won Kim |
| collection | DOAJ |
| description | <i>Background</i>: Acute mesenteric ischemia (AMI) is a life-threatening condition, and in 50% of patients, AMI is caused by acute superior mesenteric artery (SMA) embolism. Endovascular treatment is increasingly being considered the primary modality in selected cases. Many studies have reported that percutaneous aspiration embolectomy using a guiding catheter and thrombolysis with recombinant tissue plasminogen activator (rtPA) are effective in treating SMA embolism. However, no reports on treating SMA embolism using rtPA administered via a microcatheter exist. <i>Case presentation</i>: A 64-year-old man with underlying atrial fibrillation presented with acute SMA embolism revealed using computed tomography (CT). rtPA (total 3 mg) was carefully administered into the occluded SMA through a microcatheter. No complications occurred, and complete revascularization of the SMA was revealed on follow-up CT. <i>Conclusions</i>: Compared with previous reports, this case report reveals that successful revascularization can be achieved using rtPA administered via a microcatheter, with a low dose of rtPA and a short duration of thrombolysis. |
| first_indexed | 2024-03-09T16:37:53Z |
| format | Article |
| id | doaj.art-22651a79ec0848a79674bb9a883be514 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-09T16:37:53Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-22651a79ec0848a79674bb9a883be5142023-11-24T14:54:34ZengMDPI AGMedicina1010-660X1648-91442023-10-015911188910.3390/medicina59111889Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case ReportYang-Won Kim0Ho-Cheol Choi1Won-Jeong Yang2Byeong-Ju Koo3Jae-Kyeong Ahn4Jeong-Pyo Lee5Jae-Bum Na6Sa-Hong Jo7Sung-Eun Park8Jung-Ho Won9Department of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon 51472, Republic of KoreaDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Republic of Korea<i>Background</i>: Acute mesenteric ischemia (AMI) is a life-threatening condition, and in 50% of patients, AMI is caused by acute superior mesenteric artery (SMA) embolism. Endovascular treatment is increasingly being considered the primary modality in selected cases. Many studies have reported that percutaneous aspiration embolectomy using a guiding catheter and thrombolysis with recombinant tissue plasminogen activator (rtPA) are effective in treating SMA embolism. However, no reports on treating SMA embolism using rtPA administered via a microcatheter exist. <i>Case presentation</i>: A 64-year-old man with underlying atrial fibrillation presented with acute SMA embolism revealed using computed tomography (CT). rtPA (total 3 mg) was carefully administered into the occluded SMA through a microcatheter. No complications occurred, and complete revascularization of the SMA was revealed on follow-up CT. <i>Conclusions</i>: Compared with previous reports, this case report reveals that successful revascularization can be achieved using rtPA administered via a microcatheter, with a low dose of rtPA and a short duration of thrombolysis.https://www.mdpi.com/1648-9144/59/11/1889acute mesenteric ischemiaembolectomyendovascular treatmentrevascularizationsuperior mesenteric arterythrombolysis |
| spellingShingle | Yang-Won Kim Ho-Cheol Choi Won-Jeong Yang Byeong-Ju Koo Jae-Kyeong Ahn Jeong-Pyo Lee Jae-Bum Na Sa-Hong Jo Sung-Eun Park Jung-Ho Won Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report Medicina acute mesenteric ischemia embolectomy endovascular treatment revascularization superior mesenteric artery thrombolysis |
| title | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
| title_full | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
| title_fullStr | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
| title_full_unstemmed | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
| title_short | Microcatheter-Directed Thrombolysis Using Recombinant Tissue Plasminogen Activator for the Treatment of Acute Superior Mesenteric Artery Embolism: A Case Report |
| title_sort | microcatheter directed thrombolysis using recombinant tissue plasminogen activator for the treatment of acute superior mesenteric artery embolism a case report |
| topic | acute mesenteric ischemia embolectomy endovascular treatment revascularization superior mesenteric artery thrombolysis |
| url | https://www.mdpi.com/1648-9144/59/11/1889 |
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