Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials

Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials

Abstract Background Triple-Negative Breast Cancer (TNBC) is a lethal subtype of breast cancer with limited treatment options. The purpose of this Network Meta-Analysis (NMA) is to compare the efficacy and safety of inhibitors of programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L...

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Bibliographic Details
Main Authors: Ibrahim Elmakaty, Ruba Abdo, Ahmed Elsabagh, Abdelrahman Elsayed, Mohammed Imad Malki
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cancer Cell International
Subjects:
PD-1/PD-L1 inhibitors
Immune checkpoint inhibitors
Overall survival
Progression-free survival
Pathological complete response
Adverse events
Online Access:https://doi.org/10.1186/s12935-023-02941-7

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