Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trial
Background: The study was aimed to compare and evaluate the clinical and radiographic outcomes of injectable platelet-rich fibrin (i-PRF) polymerized with hydroxyapatite (HA) bone graft and HA bone graft alone for treating three-wall intrabony defects (IBDs). Materials and Methods: The trial was pla...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Indian Society of Periodontology |
| Subjects: | |
| Online Access: | http://www.jisponline.com/article.asp?issn=0972-124X;year=2023;volume=27;issue=2;spage=174;epage=179;aulast=Chaudhary |
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| author | Bharti Chaudhary Rika Singh R G Shiva Manjunath Sai Karthikeyan Sai Subramanyam |
| author_facet | Bharti Chaudhary Rika Singh R G Shiva Manjunath Sai Karthikeyan Sai Subramanyam |
| author_sort | Bharti Chaudhary |
| collection | DOAJ |
| description | Background: The study was aimed to compare and evaluate the clinical and radiographic outcomes of injectable platelet-rich fibrin (i-PRF) polymerized with hydroxyapatite (HA) bone graft and HA bone graft alone for treating three-wall intrabony defects (IBDs). Materials and Methods: The trial was planned as a randomized, prospective clinico-radiographic study with inclusion of 34 three-wall IBDs in patients with stage III periodontitis. IBDs were assigned randomly to one of the groups, i.e., Group I – experimental (i-PRF + HA) and Group II – control (HA alone). At baseline and 6 and 9-month intervals, both the clinical and radiographic measurements were taken and baseline and 9-month data were tabulated and imported into SPSS 22 software. Student unpaired and paired t- tests were used to find significant differences (p<0.05). Results: Both the groups showed substantial changes in all clinical and radiographic measures on comparison from baseline values. On intergroup comparison, the i-PRF + HA group reported significantly higher original defect resolution and original defect fill as compared to the HA group. Conclusion: i-PRF polymerized with HA graft has shown better results as compared to HA graft alone in three-wall IBDs and therefore can be used as a better possible alternative for the treatment of three-wall IBDs. |
| first_indexed | 2024-03-12T22:36:11Z |
| format | Article |
| id | doaj.art-2269bbab641d423789bda8f1a15c01d2 |
| institution | Directory Open Access Journal |
| issn | 0972-124X |
| language | English |
| last_indexed | 2024-03-12T22:36:11Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Periodontology |
| spelling | doaj.art-2269bbab641d423789bda8f1a15c01d22023-07-21T11:46:01ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2023-01-0127217417910.4103/jisp.jisp_268_22Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trialBharti ChaudharyRika SinghR G Shiva ManjunathSai Karthikeyan Sai SubramanyamBackground: The study was aimed to compare and evaluate the clinical and radiographic outcomes of injectable platelet-rich fibrin (i-PRF) polymerized with hydroxyapatite (HA) bone graft and HA bone graft alone for treating three-wall intrabony defects (IBDs). Materials and Methods: The trial was planned as a randomized, prospective clinico-radiographic study with inclusion of 34 three-wall IBDs in patients with stage III periodontitis. IBDs were assigned randomly to one of the groups, i.e., Group I – experimental (i-PRF + HA) and Group II – control (HA alone). At baseline and 6 and 9-month intervals, both the clinical and radiographic measurements were taken and baseline and 9-month data were tabulated and imported into SPSS 22 software. Student unpaired and paired t- tests were used to find significant differences (p<0.05). Results: Both the groups showed substantial changes in all clinical and radiographic measures on comparison from baseline values. On intergroup comparison, the i-PRF + HA group reported significantly higher original defect resolution and original defect fill as compared to the HA group. Conclusion: i-PRF polymerized with HA graft has shown better results as compared to HA graft alone in three-wall IBDs and therefore can be used as a better possible alternative for the treatment of three-wall IBDs.http://www.jisponline.com/article.asp?issn=0972-124X;year=2023;volume=27;issue=2;spage=174;epage=179;aulast=Chaudharyalveolar bone defectbone graftinjectable platelet-rich fibrinintrabony defectperiodontal pocketregeneration |
| spellingShingle | Bharti Chaudhary Rika Singh R G Shiva Manjunath Sai Karthikeyan Sai Subramanyam Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trial Journal of Indian Society of Periodontology alveolar bone defect bone graft injectable platelet-rich fibrin intrabony defect periodontal pocket regeneration |
| title | Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trial |
| title_full | Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trial |
| title_fullStr | Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trial |
| title_full_unstemmed | Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trial |
| title_short | Injectable platelet-rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three-wall intrabony defects: A randomized control clinical trial |
| title_sort | injectable platelet rich fibrin polymerized with hydroxyapatite bone graft for the treatment of three wall intrabony defects a randomized control clinical trial |
| topic | alveolar bone defect bone graft injectable platelet-rich fibrin intrabony defect periodontal pocket regeneration |
| url | http://www.jisponline.com/article.asp?issn=0972-124X;year=2023;volume=27;issue=2;spage=174;epage=179;aulast=Chaudhary |
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