Probucol prevents oxidative injury to endothelial cells.
We evaluated the effect of the antioxidant, probucol, on the cytotoxic effects of oxidized low density lipoprotein (OX-LDL) or of cumene hydroperoxide (CumOOH) on cultured bovine endothelial cells (EC). The addition of CumOOH to EC caused the release of lactate dehydrogenase and the accumulation of...
Main Authors: | M Kuzuya, M Naito, C Funaki, T Hayashi, K Asai, F Kuzuya |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
1991-02-01
|
Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520420802 |
Similar Items
-
The therapeutic potential of probucol and probucol analogues in neurodegenerative diseases
by: Arazu Sharif, et al.
Published: (2024-01-01) -
Probucol attenuates hyperoxia-induced lung injury in mice.
by: Tomonobu Kawaguchi, et al.
Published: (2017-01-01) -
Probucol promotes osteoblasts differentiation and prevents osteoporosis development through reducing oxidative stress
by: Zhou-Shan Tao, et al.
Published: (2022-06-01) -
Intermittent high glucose implements stress-induced senescence in human vascular endothelial cells: role of superoxide production by NADPH oxidase.
by: Morihiko Maeda, et al.
Published: (2015-01-01) -
Probucol Protects Endothelial Progenitor Cells Against Oxidized Low-Density Lipoprotein via Suppression of Reactive Oxygen Species Formation In Vivo
by: Qingbin Zhang, et al.
Published: (2016-06-01)