Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial

Abstract Background This study aimed to evaluate the efficacy of ozonized water on pain, oedema and trismus after impacted third molar mandibular surgeries when compared to double distilled water. A randomized triple blind trial was conducted. Methods Patients with third molars class II-B of Pell-Gr...

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Main Authors: José Cristiano Ramos Glória, Dhelfeson Willya Douglas-de-Oliveira, Larissa Doalla Almeida e Silva, Saulo Gabriel Moreira Falci, Cássio Roberto Rocha dos Santos
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-020-1029-5
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author José Cristiano Ramos Glória
Dhelfeson Willya Douglas-de-Oliveira
Larissa Doalla Almeida e Silva
Saulo Gabriel Moreira Falci
Cássio Roberto Rocha dos Santos
author_facet José Cristiano Ramos Glória
Dhelfeson Willya Douglas-de-Oliveira
Larissa Doalla Almeida e Silva
Saulo Gabriel Moreira Falci
Cássio Roberto Rocha dos Santos
author_sort José Cristiano Ramos Glória
collection DOAJ
description Abstract Background This study aimed to evaluate the efficacy of ozonized water on pain, oedema and trismus after impacted third molar mandibular surgeries when compared to double distilled water. A randomized triple blind trial was conducted. Methods Patients with third molars class II-B of Pell-Gregory were included, and surgical extraction was performed. Irrigation was done with ozonized (group 1) or double distilled water (group 2). The type of irrigation and the side to be operated were randomized. Neither the patients nor the operator or evaluator were aware of the irrigation solution. Pain, oedema and trismus were evaluated at baseline, 24-h, 48-h, 72-h and 7-days after treatment. The data were evaluated by Friedman, Wilcoxon, Mann-Whitney tests, and size effect. Results It was included 8 men and 12 women, with a mean age of 20.9y.o. The initial pain mean was 7.94 (±12.81) (group 1) and 5.50 (±9.12) (group 2) (p > 0,05). There was a statistically significant reduction of pain, oedema and trismus in intragroup analysis (p < 0.05). There was no statistically significant difference (p > 0.05) when comparing the oedema and trismus between groups. The size effect ranged from small (0.23) to large (1.29). Conclusions It was concluded that ozonized water was compatible as irrigation method, not inferior to double distilled water, and had satisfactory effects on management of pain, oedema and trismus after surgical removal of the third molar. Trial registration This clinical trial was registered in ClinicalTrials.gov NCT03501225 on April 18, 2018.
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spelling doaj.art-226ffee0b95848ffa3c2de7ea4f9d7882022-12-21T23:46:57ZengBMCBMC Oral Health1472-68312020-02-012011910.1186/s12903-020-1029-5Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trialJosé Cristiano Ramos Glória0Dhelfeson Willya Douglas-de-Oliveira1Larissa Doalla Almeida e Silva2Saulo Gabriel Moreira Falci3Cássio Roberto Rocha dos Santos4Departament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysAbstract Background This study aimed to evaluate the efficacy of ozonized water on pain, oedema and trismus after impacted third molar mandibular surgeries when compared to double distilled water. A randomized triple blind trial was conducted. Methods Patients with third molars class II-B of Pell-Gregory were included, and surgical extraction was performed. Irrigation was done with ozonized (group 1) or double distilled water (group 2). The type of irrigation and the side to be operated were randomized. Neither the patients nor the operator or evaluator were aware of the irrigation solution. Pain, oedema and trismus were evaluated at baseline, 24-h, 48-h, 72-h and 7-days after treatment. The data were evaluated by Friedman, Wilcoxon, Mann-Whitney tests, and size effect. Results It was included 8 men and 12 women, with a mean age of 20.9y.o. The initial pain mean was 7.94 (±12.81) (group 1) and 5.50 (±9.12) (group 2) (p > 0,05). There was a statistically significant reduction of pain, oedema and trismus in intragroup analysis (p < 0.05). There was no statistically significant difference (p > 0.05) when comparing the oedema and trismus between groups. The size effect ranged from small (0.23) to large (1.29). Conclusions It was concluded that ozonized water was compatible as irrigation method, not inferior to double distilled water, and had satisfactory effects on management of pain, oedema and trismus after surgical removal of the third molar. Trial registration This clinical trial was registered in ClinicalTrials.gov NCT03501225 on April 18, 2018.https://doi.org/10.1186/s12903-020-1029-5OzoneThird molarOral surgeryPainSwellingTrismus
spellingShingle José Cristiano Ramos Glória
Dhelfeson Willya Douglas-de-Oliveira
Larissa Doalla Almeida e Silva
Saulo Gabriel Moreira Falci
Cássio Roberto Rocha dos Santos
Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial
BMC Oral Health
Ozone
Third molar
Oral surgery
Pain
Swelling
Trismus
title Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial
title_full Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial
title_fullStr Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial
title_full_unstemmed Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial
title_short Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial
title_sort influence of ozonized water on pain oedema and trismus during impacted third molar surgery a randomized triple blind clinical trial
topic Ozone
Third molar
Oral surgery
Pain
Swelling
Trismus
url https://doi.org/10.1186/s12903-020-1029-5
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