Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial
Abstract Background This study aimed to evaluate the efficacy of ozonized water on pain, oedema and trismus after impacted third molar mandibular surgeries when compared to double distilled water. A randomized triple blind trial was conducted. Methods Patients with third molars class II-B of Pell-Gr...
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BMC
2020-02-01
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Series: | BMC Oral Health |
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Online Access: | https://doi.org/10.1186/s12903-020-1029-5 |
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author | José Cristiano Ramos Glória Dhelfeson Willya Douglas-de-Oliveira Larissa Doalla Almeida e Silva Saulo Gabriel Moreira Falci Cássio Roberto Rocha dos Santos |
author_facet | José Cristiano Ramos Glória Dhelfeson Willya Douglas-de-Oliveira Larissa Doalla Almeida e Silva Saulo Gabriel Moreira Falci Cássio Roberto Rocha dos Santos |
author_sort | José Cristiano Ramos Glória |
collection | DOAJ |
description | Abstract Background This study aimed to evaluate the efficacy of ozonized water on pain, oedema and trismus after impacted third molar mandibular surgeries when compared to double distilled water. A randomized triple blind trial was conducted. Methods Patients with third molars class II-B of Pell-Gregory were included, and surgical extraction was performed. Irrigation was done with ozonized (group 1) or double distilled water (group 2). The type of irrigation and the side to be operated were randomized. Neither the patients nor the operator or evaluator were aware of the irrigation solution. Pain, oedema and trismus were evaluated at baseline, 24-h, 48-h, 72-h and 7-days after treatment. The data were evaluated by Friedman, Wilcoxon, Mann-Whitney tests, and size effect. Results It was included 8 men and 12 women, with a mean age of 20.9y.o. The initial pain mean was 7.94 (±12.81) (group 1) and 5.50 (±9.12) (group 2) (p > 0,05). There was a statistically significant reduction of pain, oedema and trismus in intragroup analysis (p < 0.05). There was no statistically significant difference (p > 0.05) when comparing the oedema and trismus between groups. The size effect ranged from small (0.23) to large (1.29). Conclusions It was concluded that ozonized water was compatible as irrigation method, not inferior to double distilled water, and had satisfactory effects on management of pain, oedema and trismus after surgical removal of the third molar. Trial registration This clinical trial was registered in ClinicalTrials.gov NCT03501225 on April 18, 2018. |
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issn | 1472-6831 |
language | English |
last_indexed | 2024-12-13T12:06:49Z |
publishDate | 2020-02-01 |
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series | BMC Oral Health |
spelling | doaj.art-226ffee0b95848ffa3c2de7ea4f9d7882022-12-21T23:46:57ZengBMCBMC Oral Health1472-68312020-02-012011910.1186/s12903-020-1029-5Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trialJosé Cristiano Ramos Glória0Dhelfeson Willya Douglas-de-Oliveira1Larissa Doalla Almeida e Silva2Saulo Gabriel Moreira Falci3Cássio Roberto Rocha dos Santos4Departament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysDepartament of Dentistry, Faculty of Biologic Sciences and Health, Federal University of Jequitinhonha and Mucuri ValleysAbstract Background This study aimed to evaluate the efficacy of ozonized water on pain, oedema and trismus after impacted third molar mandibular surgeries when compared to double distilled water. A randomized triple blind trial was conducted. Methods Patients with third molars class II-B of Pell-Gregory were included, and surgical extraction was performed. Irrigation was done with ozonized (group 1) or double distilled water (group 2). The type of irrigation and the side to be operated were randomized. Neither the patients nor the operator or evaluator were aware of the irrigation solution. Pain, oedema and trismus were evaluated at baseline, 24-h, 48-h, 72-h and 7-days after treatment. The data were evaluated by Friedman, Wilcoxon, Mann-Whitney tests, and size effect. Results It was included 8 men and 12 women, with a mean age of 20.9y.o. The initial pain mean was 7.94 (±12.81) (group 1) and 5.50 (±9.12) (group 2) (p > 0,05). There was a statistically significant reduction of pain, oedema and trismus in intragroup analysis (p < 0.05). There was no statistically significant difference (p > 0.05) when comparing the oedema and trismus between groups. The size effect ranged from small (0.23) to large (1.29). Conclusions It was concluded that ozonized water was compatible as irrigation method, not inferior to double distilled water, and had satisfactory effects on management of pain, oedema and trismus after surgical removal of the third molar. Trial registration This clinical trial was registered in ClinicalTrials.gov NCT03501225 on April 18, 2018.https://doi.org/10.1186/s12903-020-1029-5OzoneThird molarOral surgeryPainSwellingTrismus |
spellingShingle | José Cristiano Ramos Glória Dhelfeson Willya Douglas-de-Oliveira Larissa Doalla Almeida e Silva Saulo Gabriel Moreira Falci Cássio Roberto Rocha dos Santos Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial BMC Oral Health Ozone Third molar Oral surgery Pain Swelling Trismus |
title | Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial |
title_full | Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial |
title_fullStr | Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial |
title_full_unstemmed | Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial |
title_short | Influence of ozonized water on pain, oedema, and trismus during impacted third molar surgery: a randomized, triple blind clinical trial |
title_sort | influence of ozonized water on pain oedema and trismus during impacted third molar surgery a randomized triple blind clinical trial |
topic | Ozone Third molar Oral surgery Pain Swelling Trismus |
url | https://doi.org/10.1186/s12903-020-1029-5 |
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