Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic position

<p><strong>Aim.</strong> Aortic valve disease is one of three most common cardiovascular problems. Aortic stenosis is responsible for 70% of valve disease. Aortic valve replacement is the most effective treatment for aortic stenosis nowadays. A traditional suture technique of aorti...

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Main Authors: A. N. Molchanov, E. M. Idov, K. V. Kondrashov, P. Yu. Chaplyuk, N. B. Shakhmaeva
Format: Article
Language:English
Published: Meshalkin National Medical Research Center 2017-11-01
Series:Патология кровообращения и кардиохирургия
Subjects:
Online Access:http://journalmeshalkin.ru/index.php/heartjournal/article/view/436
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author A. N. Molchanov
E. M. Idov
K. V. Kondrashov
P. Yu. Chaplyuk
N. B. Shakhmaeva
author_facet A. N. Molchanov
E. M. Idov
K. V. Kondrashov
P. Yu. Chaplyuk
N. B. Shakhmaeva
author_sort A. N. Molchanov
collection DOAJ
description <p><strong>Aim.</strong> Aortic valve disease is one of three most common cardiovascular problems. Aortic stenosis is responsible for 70% of valve disease. Aortic valve replacement is the most effective treatment for aortic stenosis nowadays. A traditional suture technique of aortic valve replacement is associated with a high risk of complications. Most of these complications occur due to ischemic aortic cross-clamp time and comorbidities. Perceval S sutureless aortic valves to be implanted in selected patients are supposed to meet the challenge. The study was aimed at assessing Perceval S sutureless aortic valve hemodynamic and clinical parameters, its intraoperative advantages and postoperative complication rates.<br /><strong>Methods.</strong> A prospective cohort study of Perceval S sutureless aortic valve implanted via J-sternotomy (n = 22) and median sternotomy (n = 10) was conducted. Early and medium postoperative clinical and functional outcomes were obtained and evaluated.<br /><strong>Results.</strong> A decrease in the transaortic gradient was observed in early (peak gradient 21.6±4.2 (p = 0.1), mean gradient 11.3±2.8 (p = 0.58)) and medium (peak gradient 15.8±5.5 (p = 0.342), mean gradient 8.8±1.9 (p = 0.54)) follow-up. The myocardial mass index tended to be reduced throughout the entire follow-up (p = 0.01). There were no prosthesis dysfunctions or biodegradation. No patient died in the postoperative period. Survival at 36 months of follow-up was 93.75%.<br /><strong>Conclusion.</strong> Perceval S xenopericardial sutureless aortic bioprostheses adequately resolve hemodynamic problems and improve left ventricle functional parameters in early and median follow-up. They may be recommended for elderly patients. Sutureless aortic valve implantation is technically feasible through J-sternotomy and contributes to an eventless follow-up.</p><p>Received 17 February 2017. Revised 16 August 2017. Accepted 28 August 2017.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> The authors declare no conflict of interest.</p>
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spelling doaj.art-2270803e9c09462d939a7daa8520411f2023-09-02T08:34:00ZengMeshalkin National Medical Research CenterПатология кровообращения и кардиохирургия1681-34722500-31192017-11-01213323910.21688/1681-3472-2017-3-32-391123Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic positionA. N. Molchanov0E. M. Idov1K. V. Kondrashov2P. Yu. Chaplyuk3N. B. Shakhmaeva4ФГБОУ ВО «Уральский государственный медицинский университет», Министерство здравоохранения Российской Федерации, Екатеринбург, Российская Федерация; ГБУЗ СО «Свердловская областная клиническая больница № 1», Екатеринбург, Российская ФедерацияФГБОУ ВО «Уральский государственный медицинский университет», Министерство здравоохранения Российской Федерации, Екатеринбург, Российская Федерация; ГБУЗ СО «Свердловская областная клиническая больница № 1», Екатеринбург, Российская ФедерацияГБУЗ СО «Свердловская областная клиническая больница № 1», Екатеринбург, Российская ФедерацияГБУЗ СО «Свердловская областная клиническая больница № 1», Екатеринбург, Российская ФедерацияГБУЗ СО «Свердловская областная клиническая больница № 1», Екатеринбург, Российская Федерация<p><strong>Aim.</strong> Aortic valve disease is one of three most common cardiovascular problems. Aortic stenosis is responsible for 70% of valve disease. Aortic valve replacement is the most effective treatment for aortic stenosis nowadays. A traditional suture technique of aortic valve replacement is associated with a high risk of complications. Most of these complications occur due to ischemic aortic cross-clamp time and comorbidities. Perceval S sutureless aortic valves to be implanted in selected patients are supposed to meet the challenge. The study was aimed at assessing Perceval S sutureless aortic valve hemodynamic and clinical parameters, its intraoperative advantages and postoperative complication rates.<br /><strong>Methods.</strong> A prospective cohort study of Perceval S sutureless aortic valve implanted via J-sternotomy (n = 22) and median sternotomy (n = 10) was conducted. Early and medium postoperative clinical and functional outcomes were obtained and evaluated.<br /><strong>Results.</strong> A decrease in the transaortic gradient was observed in early (peak gradient 21.6±4.2 (p = 0.1), mean gradient 11.3±2.8 (p = 0.58)) and medium (peak gradient 15.8±5.5 (p = 0.342), mean gradient 8.8±1.9 (p = 0.54)) follow-up. The myocardial mass index tended to be reduced throughout the entire follow-up (p = 0.01). There were no prosthesis dysfunctions or biodegradation. No patient died in the postoperative period. Survival at 36 months of follow-up was 93.75%.<br /><strong>Conclusion.</strong> Perceval S xenopericardial sutureless aortic bioprostheses adequately resolve hemodynamic problems and improve left ventricle functional parameters in early and median follow-up. They may be recommended for elderly patients. Sutureless aortic valve implantation is technically feasible through J-sternotomy and contributes to an eventless follow-up.</p><p>Received 17 February 2017. Revised 16 August 2017. Accepted 28 August 2017.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> The authors declare no conflict of interest.</p>http://journalmeshalkin.ru/index.php/heartjournal/article/view/436хирургическое лечение аортальных пороковаортальный стенозбесшовный аортальный биологический клапан Perceval S
spellingShingle A. N. Molchanov
E. M. Idov
K. V. Kondrashov
P. Yu. Chaplyuk
N. B. Shakhmaeva
Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic position
Патология кровообращения и кардиохирургия
хирургическое лечение аортальных пороков
аортальный стеноз
бесшовный аортальный биологический клапан Perceval S
title Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic position
title_full Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic position
title_fullStr Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic position
title_full_unstemmed Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic position
title_short Clinical and hemodynamic outcomes of Perceval S sutureless bioprostheses implanted through a mini-approach in the aortic position
title_sort clinical and hemodynamic outcomes of perceval s sutureless bioprostheses implanted through a mini approach in the aortic position
topic хирургическое лечение аортальных пороков
аортальный стеноз
бесшовный аортальный биологический клапан Perceval S
url http://journalmeshalkin.ru/index.php/heartjournal/article/view/436
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