Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance

Inheritance of gene expression states is fundamental for cells to ‘remember’ past events, such as environmental or developmental cues. The conserved Polycomb Repressive Complex 2 (PRC2) maintains epigenetic repression of many genes in animals and plants and modifies chromatin at its targets. Histone...

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Bibliographic Details
Main Authors: Scott Berry, Matthew Hartley, Tjelvar S G Olsson, Caroline Dean, Martin Howard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/07205