Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.

BACKGROUND:Numerous studies have evaluated the efficacy of interventions to reduce risk for sexually transmitted infections in adolescents in recent years, but their global effects remain unknown since 2008, the last date of a comprehensive review of prior studies. AIMS:This study aims at evaluating...

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Main Authors: Alexandra Morales, José P Espada, Mireia Orgilés, Silvia Escribano, Blair T Johnson, Marguerita Lightfoot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6023153?pdf=render
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author Alexandra Morales
José P Espada
Mireia Orgilés
Silvia Escribano
Blair T Johnson
Marguerita Lightfoot
author_facet Alexandra Morales
José P Espada
Mireia Orgilés
Silvia Escribano
Blair T Johnson
Marguerita Lightfoot
author_sort Alexandra Morales
collection DOAJ
description BACKGROUND:Numerous studies have evaluated the efficacy of interventions to reduce risk for sexually transmitted infections in adolescents in recent years, but their global effects remain unknown since 2008, the last date of a comprehensive review of prior studies. AIMS:This study aims at evaluating the efficacy of interventions to promote sexual health, reduce STIs and unplanned pregnancies targeted to adolescents available after 2008; and analyzing the moderators of their global efficacy. METHODS:We searched electronic databases and manual searches of some journals focused on STIs in May 2016. The studies evaluated the efficacy of interventions to reduce sexual risk in adolescents (age range: 11-19) anywhere in the world. Effect size of the relevant outcomes for sexual risk was calculated for every study. Analyses incorporated random-effect assumptions for each outcome. The homogeneity in the results was examined with the I2 statistic and its associated 95% confident interval. RESULTS:Data from 63 studies (59,795 participants) were analyzed for behavioral and non-behavioral outcomes. In the short term, interventions had a positive impact in sexual health-related knowledge (Hedges'g = 1.01), attitudes (g = 0.29), self-efficacy toward condom use (g = 0.22), intention to refuse sex (g = 0.56), condom use intention (g = 0.46), and condom use (g = 0.38). In the medium term, positive effects observed at the short-term were maintained, although effect size significantly decreased in all variables. In the long term, interventions improved condom use (g = 0.47). Moderators of the efficacy are discussed. CONCLUSIONS:Sexual health promotion interventions are effective to promote sexual health through increasing condom use. Effects on non-behavioral variables tend to decrease over time, while condom use increased in the long-term. Interventions should focus on the long-term efficacy, especially in behavioral and biological measures.
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spelling doaj.art-22814ea45de942b6bdc72668606cce442022-12-22T00:53:50ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01136e019942110.1371/journal.pone.0199421Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.Alexandra MoralesJosé P EspadaMireia OrgilésSilvia EscribanoBlair T JohnsonMarguerita LightfootBACKGROUND:Numerous studies have evaluated the efficacy of interventions to reduce risk for sexually transmitted infections in adolescents in recent years, but their global effects remain unknown since 2008, the last date of a comprehensive review of prior studies. AIMS:This study aims at evaluating the efficacy of interventions to promote sexual health, reduce STIs and unplanned pregnancies targeted to adolescents available after 2008; and analyzing the moderators of their global efficacy. METHODS:We searched electronic databases and manual searches of some journals focused on STIs in May 2016. The studies evaluated the efficacy of interventions to reduce sexual risk in adolescents (age range: 11-19) anywhere in the world. Effect size of the relevant outcomes for sexual risk was calculated for every study. Analyses incorporated random-effect assumptions for each outcome. The homogeneity in the results was examined with the I2 statistic and its associated 95% confident interval. RESULTS:Data from 63 studies (59,795 participants) were analyzed for behavioral and non-behavioral outcomes. In the short term, interventions had a positive impact in sexual health-related knowledge (Hedges'g = 1.01), attitudes (g = 0.29), self-efficacy toward condom use (g = 0.22), intention to refuse sex (g = 0.56), condom use intention (g = 0.46), and condom use (g = 0.38). In the medium term, positive effects observed at the short-term were maintained, although effect size significantly decreased in all variables. In the long term, interventions improved condom use (g = 0.47). Moderators of the efficacy are discussed. CONCLUSIONS:Sexual health promotion interventions are effective to promote sexual health through increasing condom use. Effects on non-behavioral variables tend to decrease over time, while condom use increased in the long-term. Interventions should focus on the long-term efficacy, especially in behavioral and biological measures.http://europepmc.org/articles/PMC6023153?pdf=render
spellingShingle Alexandra Morales
José P Espada
Mireia Orgilés
Silvia Escribano
Blair T Johnson
Marguerita Lightfoot
Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.
PLoS ONE
title Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.
title_full Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.
title_fullStr Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.
title_full_unstemmed Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.
title_short Interventions to reduce risk for sexually transmitted infections in adolescents: A meta-analysis of trials, 2008-2016.
title_sort interventions to reduce risk for sexually transmitted infections in adolescents a meta analysis of trials 2008 2016
url http://europepmc.org/articles/PMC6023153?pdf=render
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