Simultaneous Dual Echo Gadolinium Enhanced MR-PET for Evaluation of PET Tracer Delivery in Altered Pathophysiology

Simultaneous Dual Echo Gadolinium Enhanced MR-PET for Evaluation of PET Tracer Delivery in Altered Pathophysiology

Efficacy of diagnostics and therapeutics for brain tumours can be modulated by vascular delivery and blood brain barrier permeability. Simultaneous dynamic gadolinium MR-PET enables independent assessment of vascular delivery and blood brain barrier integrity in a brain tumour animal model in the pr...

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Bibliographic Details
Main Authors: Gary J Cowin, Karine Mardon, Zachary H. Houston, Rajiv Bhalla, Damion H. R. Stimson, Kristofer J. Thurecht, Ian M. Brereton
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Physics
Subjects:
MR-PET
gadolinium contrast agents
PET tracer delivery
T2∗
T1
blood brain barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2022.759749/full

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