A Common Neuronal Ensemble in the Lateral Habenula Regulates Ciprofol Anesthesia in Mice

A Common Neuronal Ensemble in the Lateral Habenula Regulates Ciprofol Anesthesia in Mice

General anesthetics were first used over 170 years ago; however, the mechanisms of how general anesthetics induce loss of consciousness (LOC) remain unclear. Ciprofol, a novel intravenous anesthetic, has been developed by incorporating cyclopropyl into the chemical structure of propofol. This modifi...

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Bibliographic Details
Main Authors: Kang Zhou, Lin-Chen Zhang, He Zhu, Bei Wen, Jia-Li Tang, Ping-Chuan Yuan, A-Fang Zhu, Yu-Guang Huang
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Pharmaceuticals
Subjects:
general anesthesia
loss of consciousness
TRAP
gene ablation
chemogenetic
Online Access:https://www.mdpi.com/1424-8247/17/3/363

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