CCR5 Targeted Cell Therapy for HIV and Prevention of Viral Escape

CCR5 Targeted Cell Therapy for HIV and Prevention of Viral Escape

Allogeneic transplantation with CCR5-delta 32 (CCR5-d32) homozygous stem cells in an HIV infected individual in 2008, led to a sustained virus control and probably eradication of HIV. Since then there has been a high degree of interest to translate this approach to a wider population. There are two...

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Bibliographic Details
Main Authors:	Gero Hütter, Josef Bodor, Scott Ledger, Maureen Boyd, Michelle Millington, Marlene Tsie, Geoff Symonds
Format:	Article
Language:	English
Published:	MDPI AG 2015-07-01
Series:	Viruses
Subjects:	HIV-1 CCR5 CCR5-delta32 tropism gene therapy viral escape chemokine receptor
Online Access:	http://www.mdpi.com/1999-4915/7/8/2816

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