Study on the possible role of the -174G>C IL-6 promoter polymorphism in predicting response to rituximab in rheumatoid arthritis

Study on the possible role of the -174G>C IL-6 promoter polymorphism in predicting response to rituximab in rheumatoid arthritis

Several studies demonstrated the efficacy of the B-cell depletion therapy with rituximab (RTX) in RA patients, including those unresponsive to anti- TNF therapy, underlying the important role of B cells in this disease (1-5). Several recent papers have demonstrated a differential effects of RTX in d...

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Bibliographic Details
Main Authors: F. Fischetti, L.M. Bambara, A. Carletto, M. Cutolo, P. Sarzi-Puttini, R. Pellerito, C. Fabro, E. Pontarini, M.A. Cimmino, P. Morassi, F. Atzeni, M. Saracco, M. Manfredi, M. Benucci, S. Lombardi, L. Quartuccio, M. Fabris, F. Curcio, E. Tonutti, S. De VIta
Format: Article
Language:English
Published: PAGEPress Publications 2011-06-01
Series:Reumatismo
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/490

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http://www.reumatismo.org/index.php/reuma/article/view/490

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