Coronary artery calcium score percentiles: data from a single center in Turkey
PURPOSE: The coronary artery calcium (CAC) score is used in decision-making for preventive medications in patients with borderline clinical risk scores. Both absolute and percentile CAC scores can be used; however, a percentile CAC score is especially useful in young patients and women. The aim of t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2024-01-01
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| Series: | Diagnostic and Interventional Radiology |
| Subjects: | |
| Online Access: |
http://www.dirjournal.org/archives/archive-detail/article-preview/coronary-artery-calcium-score-percentiles-data-fro/60604
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| _version_ | 1797361126705463296 |
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| author | Gülsüm Kılıçkap Halil Tekdemir Kübra Bahadır Numan İlteriş Çevik Betül Akdal Dölek Murat Vural |
| author_facet | Gülsüm Kılıçkap Halil Tekdemir Kübra Bahadır Numan İlteriş Çevik Betül Akdal Dölek Murat Vural |
| author_sort | Gülsüm Kılıçkap |
| collection | DOAJ |
| description | PURPOSE: The coronary artery calcium (CAC) score is used in decision-making for preventive medications in patients with borderline clinical risk scores. Both absolute and percentile CAC scores can be used; however, a percentile CAC score is especially useful in young patients and women. The aim of this study is to present CAC score percentiles across age categories in women and men using a large database. METHODS: Bilkent City Hospital database was screened for patients who underwent CAC score measurements between January 2021 and March 2022. Of the 4,487 patients, 546 were excluded due to 1) a history of coronary stent implantation or bypass surgery or 2) missing information regarding a history of revascularization or calcium scores. Therefore, the final study population included 3,941 participants. The percentiles for age categories within each sex were tabulated, and percentile plots were created for each sex using locally weighted scatterplot smoothing regression. RESULTS: The proportion of men included in the study was higher compared with that of women (57.09% vs. 42.91%). The mean age was 52.20 ± 11.11 years, and it was higher in women than in men (54.07 ± 10.47 vs. 50.80 ± 11.37, respectively; P < 0.001). A zero CAC score was observed in 2,381 (60.42%) patients; the percentage was higher in women than in men (68.60% vs. 54.27%; P < 0.001). When the cut-off value for the high-risk category was taken as the 75<sup>th</sup> percentile, a non-zero CAC score directly assigned a patient into the high-risk category in women aged <55 years and men aged <45 years. Percentile plots were also provided for each sex. CONCLUSION: In this large-scale study, including patients referred for CAC scoring and/or coronary computed tomography angiography, CAC score percentiles were provided for women and men across the selected age categories which may be in therapeutic decision-making. As an approximate rule of thumb, a non-zero CAC score corresponds to the high-risk category in women aged <55 years and in men aged <45 years. |
| first_indexed | 2024-03-08T15:49:29Z |
| format | Article |
| id | doaj.art-229928a2cbb04cf887dd6860dcae9fa3 |
| institution | Directory Open Access Journal |
| issn | 1305-3612 |
| language | English |
| last_indexed | 2024-03-08T15:49:29Z |
| publishDate | 2024-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-229928a2cbb04cf887dd6860dcae9fa32024-01-09T06:45:02ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-36122024-01-01301212710.4274/dir.2023.23219613049054Coronary artery calcium score percentiles: data from a single center in TurkeyGülsüm Kılıçkap0Halil Tekdemir1Kübra Bahadır2Numan İlteriş Çevik3Betül Akdal Dölek4Murat Vural5 Ankara Bilkent City Hospital, Clinic of Radiology, Ankara, Turkey Ankara Bilkent City Hospital, Clinic of Radiology, Ankara, Turkey Ankara Bilkent City Hospital, Clinic of Radiology, Ankara, Turkey Ankara Bilkent City Hospital, Clinic of Radiology, Ankara, Turkey Ankara Bilkent City Hospital, Clinic of Radiology, Ankara, Turkey Ankara Bilkent City Hospital, Clinic of Radiology, Ankara, Turkey PURPOSE: The coronary artery calcium (CAC) score is used in decision-making for preventive medications in patients with borderline clinical risk scores. Both absolute and percentile CAC scores can be used; however, a percentile CAC score is especially useful in young patients and women. The aim of this study is to present CAC score percentiles across age categories in women and men using a large database. METHODS: Bilkent City Hospital database was screened for patients who underwent CAC score measurements between January 2021 and March 2022. Of the 4,487 patients, 546 were excluded due to 1) a history of coronary stent implantation or bypass surgery or 2) missing information regarding a history of revascularization or calcium scores. Therefore, the final study population included 3,941 participants. The percentiles for age categories within each sex were tabulated, and percentile plots were created for each sex using locally weighted scatterplot smoothing regression. RESULTS: The proportion of men included in the study was higher compared with that of women (57.09% vs. 42.91%). The mean age was 52.20 ± 11.11 years, and it was higher in women than in men (54.07 ± 10.47 vs. 50.80 ± 11.37, respectively; P < 0.001). A zero CAC score was observed in 2,381 (60.42%) patients; the percentage was higher in women than in men (68.60% vs. 54.27%; P < 0.001). When the cut-off value for the high-risk category was taken as the 75<sup>th</sup> percentile, a non-zero CAC score directly assigned a patient into the high-risk category in women aged <55 years and men aged <45 years. Percentile plots were also provided for each sex. CONCLUSION: In this large-scale study, including patients referred for CAC scoring and/or coronary computed tomography angiography, CAC score percentiles were provided for women and men across the selected age categories which may be in therapeutic decision-making. As an approximate rule of thumb, a non-zero CAC score corresponds to the high-risk category in women aged <55 years and in men aged <45 years. http://www.dirjournal.org/archives/archive-detail/article-preview/coronary-artery-calcium-score-percentiles-data-fro/60604 coronary arterycalcium scorecomputed tomographypercentilescardiovascular risk scores |
| spellingShingle | Gülsüm Kılıçkap Halil Tekdemir Kübra Bahadır Numan İlteriş Çevik Betül Akdal Dölek Murat Vural Coronary artery calcium score percentiles: data from a single center in Turkey Diagnostic and Interventional Radiology coronary artery calcium score computed tomography percentiles cardiovascular risk scores |
| title | Coronary artery calcium score percentiles: data from a single center in Turkey |
| title_full | Coronary artery calcium score percentiles: data from a single center in Turkey |
| title_fullStr | Coronary artery calcium score percentiles: data from a single center in Turkey |
| title_full_unstemmed | Coronary artery calcium score percentiles: data from a single center in Turkey |
| title_short | Coronary artery calcium score percentiles: data from a single center in Turkey |
| title_sort | coronary artery calcium score percentiles data from a single center in turkey |
| topic | coronary artery calcium score computed tomography percentiles cardiovascular risk scores |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/coronary-artery-calcium-score-percentiles-data-fro/60604
|
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