Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract
Bacteriocins are ribosomal-synthesized hydrophobic antimicrobial peptides with a broad antimicrobial spectrum of action. Gram-positive bacteria are the main source of bacteriocins. Bacteriocins of different classes acting on Gram-positive and Gram-negative bacteria use different molecular mechanisms...
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| Format: | Article |
| Language: | English |
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Zaslavsky O.Yu.
2017-10-01
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| Series: | Zdorovʹe Rebenka |
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| Online Access: | http://childshealth.zaslavsky.com.ua/article/view/116187 |
| _version_ | 1818998481580195840 |
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| author | А.Е. Abaturov Т.А. Kryuchko |
| author_facet | А.Е. Abaturov Т.А. Kryuchko |
| author_sort | А.Е. Abaturov |
| collection | DOAJ |
| description | Bacteriocins are ribosomal-synthesized hydrophobic antimicrobial peptides with a broad antimicrobial spectrum of action. Gram-positive bacteria are the main source of bacteriocins. Bacteriocins of different classes acting on Gram-positive and Gram-negative bacteria use different molecular mechanisms, the functioning of which leads to disruption of the integrity of the cell wall or inhibition of the synthesis of nucleic acids and proteins of targeted bacteria. Currently, more than 100 lantibiotic peptides are described in the literature. Many of them are used to develop future medicines. Several lantibiotics are currently undergoing clinical and preclinical trials, including bioengineering lantibiotics, which can play a key role in overcoming the antibiotic resistance of bacterial pathogens. |
| first_indexed | 2024-12-20T22:02:13Z |
| format | Article |
| id | doaj.art-229e91cc0c5c463ab11a68130a376e7c |
| institution | Directory Open Access Journal |
| issn | 2224-0551 2307-1168 |
| language | English |
| last_indexed | 2024-12-20T22:02:13Z |
| publishDate | 2017-10-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Zdorovʹe Rebenka |
| spelling | doaj.art-229e91cc0c5c463ab11a68130a376e7c2022-12-21T19:25:20ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682017-10-0112781281910.22141/2224-0551.12.7.2017.116187116187Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tractА.Е. Abaturov0Т.А. Kryuchko1SI “Dnipropetrovsk Medical academy of Ministry of Health of Ukraine”, Dnipro, UkraineHSEIU “Ukrainian Medical Stomatological Academy”, Poltava, UkraineBacteriocins are ribosomal-synthesized hydrophobic antimicrobial peptides with a broad antimicrobial spectrum of action. Gram-positive bacteria are the main source of bacteriocins. Bacteriocins of different classes acting on Gram-positive and Gram-negative bacteria use different molecular mechanisms, the functioning of which leads to disruption of the integrity of the cell wall or inhibition of the synthesis of nucleic acids and proteins of targeted bacteria. Currently, more than 100 lantibiotic peptides are described in the literature. Many of them are used to develop future medicines. Several lantibiotics are currently undergoing clinical and preclinical trials, including bioengineering lantibiotics, which can play a key role in overcoming the antibiotic resistance of bacterial pathogens.http://childshealth.zaslavsky.com.ua/article/view/116187infectious diseases of the respiratory tractchildrenbacteriocins |
| spellingShingle | А.Е. Abaturov Т.А. Kryuchko Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract Zdorovʹe Rebenka infectious diseases of the respiratory tract children bacteriocins |
| title | Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract |
| title_full | Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract |
| title_fullStr | Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract |
| title_full_unstemmed | Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract |
| title_short | Potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract |
| title_sort | potential value of bacteriocins in the etiological treatment of infectious diseases of the respiratory tract |
| topic | infectious diseases of the respiratory tract children bacteriocins |
| url | http://childshealth.zaslavsky.com.ua/article/view/116187 |
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