Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature

<p>Abstract</p> <p>Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has...

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Main Authors: Perrella Eleonora, Picardi Antonio, Carassiti Massimiliano, Crucitti Pierfilippo, Uwechie Valentina, Santini Daniele, Di Matteo Francesco, Zardi Enrico M, Caricato Marco, Tonini Giuseppe, Coppola Roberto, Afeltra Antonella
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/27/1/28
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author Perrella Eleonora
Picardi Antonio
Carassiti Massimiliano
Crucitti Pierfilippo
Uwechie Valentina
Santini Daniele
Di Matteo Francesco
Zardi Enrico M
Caricato Marco
Tonini Giuseppe
Coppola Roberto
Afeltra Antonella
author_facet Perrella Eleonora
Picardi Antonio
Carassiti Massimiliano
Crucitti Pierfilippo
Uwechie Valentina
Santini Daniele
Di Matteo Francesco
Zardi Enrico M
Caricato Marco
Tonini Giuseppe
Coppola Roberto
Afeltra Antonella
author_sort Perrella Eleonora
collection DOAJ
description <p>Abstract</p> <p>Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare lethal complication of intra-arterial PEI, another modality for treating HCCs. In this minireview, we analyze the literature concerning the development of acute pancreatitis after PEI. Pathogenesis of pancreatitis from opioids and ethanol is also addressed. Treatment with opioids to reduce the patient's abdominal pain after PEI in combination with the PEI itself may lead to direct toxic effects, thus favouring the development of pancreatitis.</p>
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spelling doaj.art-229f263a30264efea2bba264c45e4c3f2022-12-21T22:11:39ZengBMCJournal of Experimental & Clinical Cancer Research1756-99662008-08-012712810.1186/1756-9966-27-28Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literaturePerrella EleonoraPicardi AntonioCarassiti MassimilianoCrucitti PierfilippoUwechie ValentinaSantini DanieleDi Matteo FrancescoZardi Enrico MCaricato MarcoTonini GiuseppeCoppola RobertoAfeltra Antonella<p>Abstract</p> <p>Deaths after percutaneous ethanol injection (PEI) into hepatocellular carcinoma (HCC) may occur within a few hours to a few days following the procedure because of hemoperitoneum and haemorrhage from oesophageal varices or hepatic insufficiency. Pancreatitis has been recently reported as a rare lethal complication of intra-arterial PEI, another modality for treating HCCs. In this minireview, we analyze the literature concerning the development of acute pancreatitis after PEI. Pathogenesis of pancreatitis from opioids and ethanol is also addressed. Treatment with opioids to reduce the patient's abdominal pain after PEI in combination with the PEI itself may lead to direct toxic effects, thus favouring the development of pancreatitis.</p>http://www.jeccr.com/content/27/1/28
spellingShingle Perrella Eleonora
Picardi Antonio
Carassiti Massimiliano
Crucitti Pierfilippo
Uwechie Valentina
Santini Daniele
Di Matteo Francesco
Zardi Enrico M
Caricato Marco
Tonini Giuseppe
Coppola Roberto
Afeltra Antonella
Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
Journal of Experimental & Clinical Cancer Research
title Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_full Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_fullStr Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_full_unstemmed Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_short Pancreatitis after percutaneous ethanol injection into HCC: a minireview of the literature
title_sort pancreatitis after percutaneous ethanol injection into hcc a minireview of the literature
url http://www.jeccr.com/content/27/1/28
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