Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib

It has been suggested that targeted therapy may potentially increase the risk of listeriosis. However, no reported cases of Listeria monocytogenes prosthetic joint infection have been documented during Janus Kinase (JAK) pathway inhibitor use. Herein, we present a 70-year-old female with rheumatoid...

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Main Authors: Chaowen Deng, Kelvin Hei-Yeung Chiu, Nan Lou, Fanfan Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1322993/full
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author Chaowen Deng
Kelvin Hei-Yeung Chiu
Nan Lou
Fanfan Xing
author_facet Chaowen Deng
Kelvin Hei-Yeung Chiu
Nan Lou
Fanfan Xing
author_sort Chaowen Deng
collection DOAJ
description It has been suggested that targeted therapy may potentially increase the risk of listeriosis. However, no reported cases of Listeria monocytogenes prosthetic joint infection have been documented during Janus Kinase (JAK) pathway inhibitor use. Herein, we present a 70-year-old female with rheumatoid arthritis who had undergone bilateral hip joint replacement and subsequently developed Listeria monocytogenes prosthetic joint infection following tofacitinib therapy. We suggest that the use of tofacitinib may potentially heighten susceptibility to listeriosis in patients afflicted with rheumatoid arthritis.
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spelling doaj.art-22a5ae379aec4eb2924c94eb68acf22b2024-01-09T04:16:33ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2024-01-011010.3389/fmed.2023.13229931322993Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinibChaowen Deng0Kelvin Hei-Yeung Chiu1Nan Lou2Fanfan Xing3Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, ChinaDepartment of Microbiology, Queen Mary Hospital, Hong Kong, Hong Kong SAR, ChinaDepartment of Orthopedics, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, ChinaDepartment of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, ChinaIt has been suggested that targeted therapy may potentially increase the risk of listeriosis. However, no reported cases of Listeria monocytogenes prosthetic joint infection have been documented during Janus Kinase (JAK) pathway inhibitor use. Herein, we present a 70-year-old female with rheumatoid arthritis who had undergone bilateral hip joint replacement and subsequently developed Listeria monocytogenes prosthetic joint infection following tofacitinib therapy. We suggest that the use of tofacitinib may potentially heighten susceptibility to listeriosis in patients afflicted with rheumatoid arthritis.https://www.frontiersin.org/articles/10.3389/fmed.2023.1322993/fullListeria monocytogenesprosthetic joint infectionrheumatoid arthritistofacitinibcase report
spellingShingle Chaowen Deng
Kelvin Hei-Yeung Chiu
Nan Lou
Fanfan Xing
Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib
Frontiers in Medicine
Listeria monocytogenes
prosthetic joint infection
rheumatoid arthritis
tofacitinib
case report
title Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib
title_full Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib
title_fullStr Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib
title_full_unstemmed Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib
title_short Case report: Occult Listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib
title_sort case report occult listeria monocytogenes invasion leading to prosthetic hip joint infection in a patient with rheumatoid arthritis taking tofacitinib
topic Listeria monocytogenes
prosthetic joint infection
rheumatoid arthritis
tofacitinib
case report
url https://www.frontiersin.org/articles/10.3389/fmed.2023.1322993/full
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