Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic Encephalopathy

Introduction: Neurological morbidities are the earliest presentation of hypoxic insult in newborns. Parents seek medical advice when they notice abnormal posture or abnormal movements or persistent cry or delayed milestones. By that time pathophysiology would have set in and would have led to irreve...

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Main Authors: Kamal Kishore Sagaria, Sunil Kumar Rao
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2019-01-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/12524/38072_CE[Ra1]_F(SL)_PF1(AGAK)_PFA(AK)_PB(NC_AG)_PN(SL).pdf
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author Kamal Kishore Sagaria
Sunil Kumar Rao
author_facet Kamal Kishore Sagaria
Sunil Kumar Rao
author_sort Kamal Kishore Sagaria
collection DOAJ
description Introduction: Neurological morbidities are the earliest presentation of hypoxic insult in newborns. Parents seek medical advice when they notice abnormal posture or abnormal movements or persistent cry or delayed milestones. By that time pathophysiology would have set in and would have led to irreversible changes in brain which subsequently manifests in developing period of brain or later. Early recognition of asphyxiated newborns and their timely referral has better neurological outcome. Aim: To describe Moro’s response in newborns with Hypoxic Ischaemic Encephalopathy (HIE) by using Ordinal scale. Materials and Methods: This was a prospective cross-sectional study conducted in a tertiary care hospital. Inclusion criteria were full term newborns with HIE. Recruited newborns were classified in different grades of HIE after initial stabilisation, two investigators were present in examination room, one investigator examined the Moro’s response while the baby was alert, active and moving the limbs by using head drop method. Whole event was recorded by second investigator and third investigator was calculating the latency interval of Moro’s response by using stopwatch with accuracy of 1/100 of a second from video recording separately. Moro’s response was assessed by ordinal scale. Results: Final analysis was done on 104 newborns, out of which 18 had absent reflex, 17 had long latency interval, 19 had normal latency interval and 50 newborns had short latency interval. Long latency of Moro response had sensitivity of 45.95%, with 50.8% of accuracy to screen deviant Moro’s response in HIE. Conclusion: Long latency interval of Moro response could be a valuable clinical sign to screen for neurological impairment in HIE.
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spelling doaj.art-22a802ccd1a94420b527431201e2d7182022-12-21T18:02:06ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2019-01-01131SC07SC0910.7860/JCDR/2019/38072.12524Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic EncephalopathyKamal Kishore Sagaria0Sunil Kumar Rao1Resident Doctor, Department of Paediatrics, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.Associate Professor, Department of Paediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.Introduction: Neurological morbidities are the earliest presentation of hypoxic insult in newborns. Parents seek medical advice when they notice abnormal posture or abnormal movements or persistent cry or delayed milestones. By that time pathophysiology would have set in and would have led to irreversible changes in brain which subsequently manifests in developing period of brain or later. Early recognition of asphyxiated newborns and their timely referral has better neurological outcome. Aim: To describe Moro’s response in newborns with Hypoxic Ischaemic Encephalopathy (HIE) by using Ordinal scale. Materials and Methods: This was a prospective cross-sectional study conducted in a tertiary care hospital. Inclusion criteria were full term newborns with HIE. Recruited newborns were classified in different grades of HIE after initial stabilisation, two investigators were present in examination room, one investigator examined the Moro’s response while the baby was alert, active and moving the limbs by using head drop method. Whole event was recorded by second investigator and third investigator was calculating the latency interval of Moro’s response by using stopwatch with accuracy of 1/100 of a second from video recording separately. Moro’s response was assessed by ordinal scale. Results: Final analysis was done on 104 newborns, out of which 18 had absent reflex, 17 had long latency interval, 19 had normal latency interval and 50 newborns had short latency interval. Long latency of Moro response had sensitivity of 45.95%, with 50.8% of accuracy to screen deviant Moro’s response in HIE. Conclusion: Long latency interval of Moro response could be a valuable clinical sign to screen for neurological impairment in HIE.https://jcdr.net/articles/PDF/12524/38072_CE[Ra1]_F(SL)_PF1(AGAK)_PFA(AK)_PB(NC_AG)_PN(SL).pdfasphyxiadeviant moro responselong latencyordinal scale
spellingShingle Kamal Kishore Sagaria
Sunil Kumar Rao
Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic Encephalopathy
Journal of Clinical and Diagnostic Research
asphyxia
deviant moro response
long latency
ordinal scale
title Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic Encephalopathy
title_full Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic Encephalopathy
title_fullStr Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic Encephalopathy
title_full_unstemmed Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic Encephalopathy
title_short Study of Latency Interval of Moro Reflex in Full-term Newborns with Hypoxic Ischaemic Encephalopathy
title_sort study of latency interval of moro reflex in full term newborns with hypoxic ischaemic encephalopathy
topic asphyxia
deviant moro response
long latency
ordinal scale
url https://jcdr.net/articles/PDF/12524/38072_CE[Ra1]_F(SL)_PF1(AGAK)_PFA(AK)_PB(NC_AG)_PN(SL).pdf
work_keys_str_mv AT kamalkishoresagaria studyoflatencyintervalofmororeflexinfulltermnewbornswithhypoxicischaemicencephalopathy
AT sunilkumarrao studyoflatencyintervalofmororeflexinfulltermnewbornswithhypoxicischaemicencephalopathy