Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes

Some transition metal complexes of nicotinamide have been prepared and characterized using melting point, conductivity measurement, infrared, electronic, HNMR and atomic absorption spectroscopic methods. . The antibacterial and antifungal studies of the metal complexes and the ligand have been eval...

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Main Authors: A Lawal, J A Obaleye, J F Adediji, S A Amolegbe, M O Bamigboye, M T Yunus- Issa
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2014-07-01
Series:Journal of Applied Sciences and Environmental Management
Subjects:
Online Access:https://www.ajol.info/index.php/jasem/article/view/105367
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author A Lawal
J A Obaleye
J F Adediji
S A Amolegbe
M O Bamigboye
M T Yunus- Issa
author_facet A Lawal
J A Obaleye
J F Adediji
S A Amolegbe
M O Bamigboye
M T Yunus- Issa
author_sort A Lawal
collection DOAJ
description Some transition metal complexes of nicotinamide have been prepared and characterized using melting point, conductivity measurement, infrared, electronic, HNMR and atomic absorption spectroscopic methods. . The antibacterial and antifungal studies of the metal complexes and the ligand have been evaluated against Escherichia coli, Staphylococcus and Bacillus subtilis , Aspergillus flavus, Aspergillus niger and penicillum species. It was found that nicotinamide formed stable metal complexes with these metal ions. The analysis of the spectroscopic data shows that nicotinamide act as monodentate, coordinating through the nitrogen atom of the pyridine ring. All the complexes exhibit 4- coordinate geometry. The results of the antimicrobial studies showed that the metal complexes have higher inhibitory activity than the original nicotinamide against the tested bacteria and fungi species. Keywords: Synthesis, Metal complexes, Nicotinamide, Antibacterial, Antifungal
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spelling doaj.art-22a8c3f065a64f8081ed4c5a2530ea9f2024-04-02T19:53:39ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992014-07-0118210.4314/jasem.v18i2.8Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal ComplexesA LawalJ A ObaleyeJ F AdedijiS A AmolegbeM O BamigboyeM T Yunus- Issa Some transition metal complexes of nicotinamide have been prepared and characterized using melting point, conductivity measurement, infrared, electronic, HNMR and atomic absorption spectroscopic methods. . The antibacterial and antifungal studies of the metal complexes and the ligand have been evaluated against Escherichia coli, Staphylococcus and Bacillus subtilis , Aspergillus flavus, Aspergillus niger and penicillum species. It was found that nicotinamide formed stable metal complexes with these metal ions. The analysis of the spectroscopic data shows that nicotinamide act as monodentate, coordinating through the nitrogen atom of the pyridine ring. All the complexes exhibit 4- coordinate geometry. The results of the antimicrobial studies showed that the metal complexes have higher inhibitory activity than the original nicotinamide against the tested bacteria and fungi species. Keywords: Synthesis, Metal complexes, Nicotinamide, Antibacterial, Antifungal https://www.ajol.info/index.php/jasem/article/view/105367SynthesisMetal complexesNicotinamideAntibacterialAntifungal
spellingShingle A Lawal
J A Obaleye
J F Adediji
S A Amolegbe
M O Bamigboye
M T Yunus- Issa
Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes
Journal of Applied Sciences and Environmental Management
Synthesis
Metal complexes
Nicotinamide
Antibacterial
Antifungal
title Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes
title_full Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes
title_fullStr Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes
title_full_unstemmed Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes
title_short Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes
title_sort synthesis characterization and antimicrobial activities of some nicotinamide metal complexes
topic Synthesis
Metal complexes
Nicotinamide
Antibacterial
Antifungal
url https://www.ajol.info/index.php/jasem/article/view/105367
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AT mobamigboye synthesischaracterizationandantimicrobialactivitiesofsomenicotinamidemetalcomplexes
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