Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes
Some transition metal complexes of nicotinamide have been prepared and characterized using melting point, conductivity measurement, infrared, electronic, HNMR and atomic absorption spectroscopic methods. . The antibacterial and antifungal studies of the metal complexes and the ligand have been eval...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)
2014-07-01
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Series: | Journal of Applied Sciences and Environmental Management |
Subjects: | |
Online Access: | https://www.ajol.info/index.php/jasem/article/view/105367 |
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author | A Lawal J A Obaleye J F Adediji S A Amolegbe M O Bamigboye M T Yunus- Issa |
author_facet | A Lawal J A Obaleye J F Adediji S A Amolegbe M O Bamigboye M T Yunus- Issa |
author_sort | A Lawal |
collection | DOAJ |
description |
Some transition metal complexes of nicotinamide have been prepared and characterized using melting point, conductivity measurement, infrared, electronic, HNMR and atomic absorption spectroscopic methods. . The antibacterial and antifungal studies of the metal complexes and the ligand have been evaluated against Escherichia coli, Staphylococcus and Bacillus subtilis , Aspergillus flavus, Aspergillus niger and penicillum species. It was found that nicotinamide formed stable metal complexes with these metal ions. The analysis of the spectroscopic data shows that nicotinamide act as monodentate, coordinating through the nitrogen atom of the pyridine ring. All the complexes exhibit 4- coordinate geometry. The results of the antimicrobial studies showed that the metal complexes have higher inhibitory activity than the original nicotinamide against the tested bacteria and fungi species.
Keywords: Synthesis, Metal complexes, Nicotinamide, Antibacterial, Antifungal
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first_indexed | 2024-04-24T14:47:52Z |
format | Article |
id | doaj.art-22a8c3f065a64f8081ed4c5a2530ea9f |
institution | Directory Open Access Journal |
issn | 2659-1502 2659-1499 |
language | English |
last_indexed | 2024-04-24T14:47:52Z |
publishDate | 2014-07-01 |
publisher | Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) |
record_format | Article |
series | Journal of Applied Sciences and Environmental Management |
spelling | doaj.art-22a8c3f065a64f8081ed4c5a2530ea9f2024-04-02T19:53:39ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992014-07-0118210.4314/jasem.v18i2.8Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal ComplexesA LawalJ A ObaleyeJ F AdedijiS A AmolegbeM O BamigboyeM T Yunus- Issa Some transition metal complexes of nicotinamide have been prepared and characterized using melting point, conductivity measurement, infrared, electronic, HNMR and atomic absorption spectroscopic methods. . The antibacterial and antifungal studies of the metal complexes and the ligand have been evaluated against Escherichia coli, Staphylococcus and Bacillus subtilis , Aspergillus flavus, Aspergillus niger and penicillum species. It was found that nicotinamide formed stable metal complexes with these metal ions. The analysis of the spectroscopic data shows that nicotinamide act as monodentate, coordinating through the nitrogen atom of the pyridine ring. All the complexes exhibit 4- coordinate geometry. The results of the antimicrobial studies showed that the metal complexes have higher inhibitory activity than the original nicotinamide against the tested bacteria and fungi species. Keywords: Synthesis, Metal complexes, Nicotinamide, Antibacterial, Antifungal https://www.ajol.info/index.php/jasem/article/view/105367SynthesisMetal complexesNicotinamideAntibacterialAntifungal |
spellingShingle | A Lawal J A Obaleye J F Adediji S A Amolegbe M O Bamigboye M T Yunus- Issa Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes Journal of Applied Sciences and Environmental Management Synthesis Metal complexes Nicotinamide Antibacterial Antifungal |
title | Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes |
title_full | Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes |
title_fullStr | Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes |
title_full_unstemmed | Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes |
title_short | Synthesis, Characterization and Antimicrobial Activities of Some Nicotinamide – metal Complexes |
title_sort | synthesis characterization and antimicrobial activities of some nicotinamide metal complexes |
topic | Synthesis Metal complexes Nicotinamide Antibacterial Antifungal |
url | https://www.ajol.info/index.php/jasem/article/view/105367 |
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