Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients
Nephron-sparing surgery (NSS) in Wilms tumor (WT) patients is a surgically challenging procedure used in highly selective cases only. Virtual resections can be used for preoperative planning of NSS to estimate the remnant renal volume (RRV) and to virtually mimic radical tumor resection. In this sin...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/29/2/66 |
| _version_ | 1797481330450104320 |
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| author | Jasper M. van der Zee Matthijs Fitski Frank F. J. Simonis Cornelis P. van de Ven Aart J. Klijn Marc H. W. A. Wijnen Alida F. W. van der Steeg |
| author_facet | Jasper M. van der Zee Matthijs Fitski Frank F. J. Simonis Cornelis P. van de Ven Aart J. Klijn Marc H. W. A. Wijnen Alida F. W. van der Steeg |
| author_sort | Jasper M. van der Zee |
| collection | DOAJ |
| description | Nephron-sparing surgery (NSS) in Wilms tumor (WT) patients is a surgically challenging procedure used in highly selective cases only. Virtual resections can be used for preoperative planning of NSS to estimate the remnant renal volume (RRV) and to virtually mimic radical tumor resection. In this single-center evaluation study, virtual resection for NSS planning and the user experience were evaluated. Virtual resection was performed in nine WT patient cases by two pediatric surgeons and one pediatric urologist. Pre- and postoperative MRI scans were used for 3D visualization. The virtual RRV was acquired after performing virtual resection and a questionnaire was used to assess the ease of use. The actual RRV was derived from the postoperative 3D visualization and compared with the derived virtual RRV. Virtual resection resulted in virtual RRVs that matched nearly perfectly with the actual RRVs. According to the questionnaire, virtual resection appeared to be straightforward and was not considered to be difficult. This study demonstrated the potential of virtual resection as a new planning tool to estimate the RRV after NSS in WT patients. Future research should further evaluate the clinical relevance of virtual resection by relating it to surgical outcome. |
| first_indexed | 2024-03-09T22:14:01Z |
| format | Article |
| id | doaj.art-22b1e297bfa94aa9b802d4eb681a73aa |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-09T22:14:01Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-22b1e297bfa94aa9b802d4eb681a73aa2023-11-23T19:26:52ZengMDPI AGCurrent Oncology1198-00521718-77292022-02-0129277778410.3390/curroncol29020066Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor PatientsJasper M. van der Zee0Matthijs Fitski1Frank F. J. Simonis2Cornelis P. van de Ven3Aart J. Klijn4Marc H. W. A. Wijnen5Alida F. W. van der Steeg6Department for Pediatric Surgery, Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The NetherlandsDepartment for Pediatric Surgery, Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The NetherlandsMagnetic Detection & Imaging, TechMed Centre, University of Twente, 7522 NB Enschede, The NetherlandsDepartment for Pediatric Surgery, Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The NetherlandsDepartment of Pediatric Urology, University Medical Center Utrecht/Wilhelmina Children’s Hospital, 3584 CX Utrecht, The NetherlandsDepartment for Pediatric Surgery, Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The NetherlandsDepartment for Pediatric Surgery, Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, The NetherlandsNephron-sparing surgery (NSS) in Wilms tumor (WT) patients is a surgically challenging procedure used in highly selective cases only. Virtual resections can be used for preoperative planning of NSS to estimate the remnant renal volume (RRV) and to virtually mimic radical tumor resection. In this single-center evaluation study, virtual resection for NSS planning and the user experience were evaluated. Virtual resection was performed in nine WT patient cases by two pediatric surgeons and one pediatric urologist. Pre- and postoperative MRI scans were used for 3D visualization. The virtual RRV was acquired after performing virtual resection and a questionnaire was used to assess the ease of use. The actual RRV was derived from the postoperative 3D visualization and compared with the derived virtual RRV. Virtual resection resulted in virtual RRVs that matched nearly perfectly with the actual RRVs. According to the questionnaire, virtual resection appeared to be straightforward and was not considered to be difficult. This study demonstrated the potential of virtual resection as a new planning tool to estimate the RRV after NSS in WT patients. Future research should further evaluate the clinical relevance of virtual resection by relating it to surgical outcome.https://www.mdpi.com/1718-7729/29/2/66Wilms tumorvirtual resectionremnant renal volumenephron-sparing surgerypartial nephrectomyremnant renal parenchyma |
| spellingShingle | Jasper M. van der Zee Matthijs Fitski Frank F. J. Simonis Cornelis P. van de Ven Aart J. Klijn Marc H. W. A. Wijnen Alida F. W. van der Steeg Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients Current Oncology Wilms tumor virtual resection remnant renal volume nephron-sparing surgery partial nephrectomy remnant renal parenchyma |
| title | Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients |
| title_full | Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients |
| title_fullStr | Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients |
| title_full_unstemmed | Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients |
| title_short | Virtual Resection: A New Tool for Preparing for Nephron-Sparing Surgery in Wilms Tumor Patients |
| title_sort | virtual resection a new tool for preparing for nephron sparing surgery in wilms tumor patients |
| topic | Wilms tumor virtual resection remnant renal volume nephron-sparing surgery partial nephrectomy remnant renal parenchyma |
| url | https://www.mdpi.com/1718-7729/29/2/66 |
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