Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger
Cardiovascular diseases (CVD) are the most important cause of morbidity and mortality in the general population. Because the high prevalence of COVID-19 and chronic Chagas disease (CCD) where the latter is endemic, all such diseases will likely be observed in the same patient. While COVID-19 can pro...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.910388/full |
| _version_ | 1828314207319228416 |
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| author | Reinaldo Bulgarelli Bestetti Edimar Alcides Bocchi Renato Bestetti Victor Sarli Issa Rosemary Aparecida Furlan-Daniel Marcelo Arruda Nakazone |
| author_facet | Reinaldo Bulgarelli Bestetti Edimar Alcides Bocchi Renato Bestetti Victor Sarli Issa Rosemary Aparecida Furlan-Daniel Marcelo Arruda Nakazone |
| author_sort | Reinaldo Bulgarelli Bestetti |
| collection | DOAJ |
| description | Cardiovascular diseases (CVD) are the most important cause of morbidity and mortality in the general population. Because the high prevalence of COVID-19 and chronic Chagas disease (CCD) where the latter is endemic, all such diseases will likely be observed in the same patient. While COVID-19 can provoke generalized endotheliitis, which can lead to a cytokine storm and a hyper-coagulable state culminating into in-site and at a distance thrombosis. Therefore, small-vessel coronary artery disease (CAD), cerebrovascular disease, thromboembolism, and arrhythmias are prominent findings in COVID-19. In CCD, small-vessel CAD, cardioembolic stroke, pulmonary embolism, heart failure and arrhythmias are frequently observed as a result of a similar but less intense mechanism. Consequently, the association of CCD and COVID-19 will likely increase the incidence of CVD. Thus, doctors on the frontline should be on the alert for this diagnostic possibility so that the proper treatment can be given without any delay. |
| first_indexed | 2024-04-13T16:41:37Z |
| format | Article |
| id | doaj.art-22b68e8d59394c34b9d1ebeef4ba3c57 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-04-13T16:41:37Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-22b68e8d59394c34b9d1ebeef4ba3c572022-12-22T02:39:12ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-06-01910.3389/fmed.2022.910388910388Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still LargerReinaldo Bulgarelli Bestetti0Edimar Alcides Bocchi1Renato Bestetti2Victor Sarli Issa3Rosemary Aparecida Furlan-Daniel4Marcelo Arruda Nakazone5Department of Medicine, Medical School, University of Ribeirão Preto, Ribeirao Preto, BrazilHeart Institute, University of São Paulo, Saõ Paulo, BrazilDepartment of Medicine, Medical School, University of Ribeirão Preto, Ribeirao Preto, BrazilDepartment of Cardiology, Antwerp University Hospital, Antwerp, BelgiumDepartment of Medicine, Medical School, University of Ribeirão Preto, Ribeirao Preto, BrazilDepartment of Cardiology and Cardiovascular Surgery, Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, BrazilCardiovascular diseases (CVD) are the most important cause of morbidity and mortality in the general population. Because the high prevalence of COVID-19 and chronic Chagas disease (CCD) where the latter is endemic, all such diseases will likely be observed in the same patient. While COVID-19 can provoke generalized endotheliitis, which can lead to a cytokine storm and a hyper-coagulable state culminating into in-site and at a distance thrombosis. Therefore, small-vessel coronary artery disease (CAD), cerebrovascular disease, thromboembolism, and arrhythmias are prominent findings in COVID-19. In CCD, small-vessel CAD, cardioembolic stroke, pulmonary embolism, heart failure and arrhythmias are frequently observed as a result of a similar but less intense mechanism. Consequently, the association of CCD and COVID-19 will likely increase the incidence of CVD. Thus, doctors on the frontline should be on the alert for this diagnostic possibility so that the proper treatment can be given without any delay.https://www.frontiersin.org/articles/10.3389/fmed.2022.910388/fullCOVID-19Chagas diseasecardiovascular diseaseSARS-CoV-2Trypanosoma cruzi |
| spellingShingle | Reinaldo Bulgarelli Bestetti Edimar Alcides Bocchi Renato Bestetti Victor Sarli Issa Rosemary Aparecida Furlan-Daniel Marcelo Arruda Nakazone Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger Frontiers in Medicine COVID-19 Chagas disease cardiovascular disease SARS-CoV-2 Trypanosoma cruzi |
| title | Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger |
| title_full | Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger |
| title_fullStr | Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger |
| title_full_unstemmed | Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger |
| title_short | Management of Cardiovascular Disease in Patients With COVID-19 and Chronic Chagas Disease: Implications to Prevent a Scourge Still Larger |
| title_sort | management of cardiovascular disease in patients with covid 19 and chronic chagas disease implications to prevent a scourge still larger |
| topic | COVID-19 Chagas disease cardiovascular disease SARS-CoV-2 Trypanosoma cruzi |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.910388/full |
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