ALKBH5 suppresses malignancy of hepatocellular carcinoma via m6A-guided epigenetic inhibition of LYPD1

ALKBH5 suppresses malignancy of hepatocellular carcinoma via m6A-guided epigenetic inhibition of LYPD1

Abstract Background N6-methyladenosine (m6A) modification is an emerging layer of epigenetic regulation which is widely implicated in the tumorigenicity of hepatocellular carcinoma (HCC), offering a novel perspective for investigating molecular pathogenesis of this disease. The role of AlkB homolog...

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Bibliographic Details
Main Authors: Yunhao Chen, Yanchun Zhao, Junru Chen, Chuanhui Peng, Yanpeng Zhang, Rongliang Tong, Qiyang Cheng, Beng Yang, Xiaode Feng, Yuejie Lu, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Molecular Cancer
Subjects:
N6-methyladenosine (m6A)
Hepatocellular carcinoma (HCC)
ALKBH5
LYPD1
Online Access:http://link.springer.com/article/10.1186/s12943-020-01239-w

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