Ventral tegmental area dopaminergic circuits participates in stress-induced chronic postsurgical pain in male mice

Ventral tegmental area dopaminergic circuits participates in stress-induced chronic postsurgical pain in male mice

Abstract Background Chronic postsurgical pain (CPP) markedly impairs patients’ quality of life. Research has shown that chronic stress may extend incisional nociception in male mice. Dopaminergic (DAergic) neurons in the ventral tegmental area (VTA) are integral to stress-related mental disorders (i...

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Bibliographic Details
Main Authors: Weizhen Liu, Wang Wang, Ziliang Wang, Ying Xing
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Neuroscience
Subjects:
Chronic postsurgical pain
Stress
Dopamine
Ventral tegmental area
Optogenetics
Chemogenetics
Online Access:https://doi.org/10.1186/s12868-023-00842-z

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