Neuroaxonal Dystrophy in a mule: first case reported
ABSTRACT A 12-month-old mule (sterile hybrid equine species) presented unspecific neurological changes (symmetric ataxia, dysmetria, conscious proprioceptive deficit and weakness). Due to poor prognosis and to the fact that a sibling from the previous generation exhibited similar clinical signs that...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Minas Gerais
2019-10-01
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| Series: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401327&tlng=en |
| _version_ | 1828133771248926720 |
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| author | L.F.A. Toledo H.L. Jerdy P.C.A.R. Silva E.C.Q. Carvalho D.A.B. Lessa |
| author_facet | L.F.A. Toledo H.L. Jerdy P.C.A.R. Silva E.C.Q. Carvalho D.A.B. Lessa |
| author_sort | L.F.A. Toledo |
| collection | DOAJ |
| description | ABSTRACT A 12-month-old mule (sterile hybrid equine species) presented unspecific neurological changes (symmetric ataxia, dysmetria, conscious proprioceptive deficit and weakness). Due to poor prognosis and to the fact that a sibling from the previous generation exhibited similar clinical signs that were not definitively diagnosed, the animal was euthanized. Diagnosis of neuroaxonal dystrophy was confirmed by anatomohistopathological analysis. This is the first clinical case of neuronal dystrophy in a mule reported in the world. The clinical and histopathological characteristics of this disease were very similar to those reported for several equine breeds. Therefore, the disease should also be considered in the diagnosis of neurological conditions in mules and donkeys. |
| first_indexed | 2024-04-11T17:23:14Z |
| format | Article |
| id | doaj.art-22c49e9800184a699edf76852eaadf3c |
| institution | Directory Open Access Journal |
| issn | 1678-4162 |
| language | English |
| last_indexed | 2024-04-11T17:23:14Z |
| publishDate | 2019-10-01 |
| publisher | Universidade Federal de Minas Gerais |
| record_format | Article |
| series | Arquivo Brasileiro de Medicina Veterinária e Zootecnia |
| spelling | doaj.art-22c49e9800184a699edf76852eaadf3c2022-12-22T04:12:25ZengUniversidade Federal de Minas GeraisArquivo Brasileiro de Medicina Veterinária e Zootecnia1678-41622019-10-017141327133010.1590/1678-4162-10375Neuroaxonal Dystrophy in a mule: first case reportedL.F.A. Toledohttps://orcid.org/0000-0002-7127-3036H.L. Jerdyhttps://orcid.org/0000-0002-2373-2453P.C.A.R. SilvaE.C.Q. Carvalhohttps://orcid.org/0000-0002-1785-8578D.A.B. Lessahttps://orcid.org/0000-0002-7123-8265ABSTRACT A 12-month-old mule (sterile hybrid equine species) presented unspecific neurological changes (symmetric ataxia, dysmetria, conscious proprioceptive deficit and weakness). Due to poor prognosis and to the fact that a sibling from the previous generation exhibited similar clinical signs that were not definitively diagnosed, the animal was euthanized. Diagnosis of neuroaxonal dystrophy was confirmed by anatomohistopathological analysis. This is the first clinical case of neuronal dystrophy in a mule reported in the world. The clinical and histopathological characteristics of this disease were very similar to those reported for several equine breeds. Therefore, the disease should also be considered in the diagnosis of neurological conditions in mules and donkeys.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401327&tlng=enataxiadegenerative myeloencephalopathydonkeyneurology |
| spellingShingle | L.F.A. Toledo H.L. Jerdy P.C.A.R. Silva E.C.Q. Carvalho D.A.B. Lessa Neuroaxonal Dystrophy in a mule: first case reported Arquivo Brasileiro de Medicina Veterinária e Zootecnia ataxia degenerative myeloencephalopathy donkey neurology |
| title | Neuroaxonal Dystrophy in a mule: first case reported |
| title_full | Neuroaxonal Dystrophy in a mule: first case reported |
| title_fullStr | Neuroaxonal Dystrophy in a mule: first case reported |
| title_full_unstemmed | Neuroaxonal Dystrophy in a mule: first case reported |
| title_short | Neuroaxonal Dystrophy in a mule: first case reported |
| title_sort | neuroaxonal dystrophy in a mule first case reported |
| topic | ataxia degenerative myeloencephalopathy donkey neurology |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401327&tlng=en |
| work_keys_str_mv | AT lfatoledo neuroaxonaldystrophyinamulefirstcasereported AT hljerdy neuroaxonaldystrophyinamulefirstcasereported AT pcarsilva neuroaxonaldystrophyinamulefirstcasereported AT ecqcarvalho neuroaxonaldystrophyinamulefirstcasereported AT dablessa neuroaxonaldystrophyinamulefirstcasereported |