The Influence of Calcium Ions on the Electrotransfer Efficiency of Plasmid DNA and Cell Viability

The Influence of Calcium Ions on the Electrotransfer Efficiency of Plasmid DNA and Cell Viability

Gene electrotransfer (GET) is recognized as a promising technique for the development of an efficient tool for gene therapy. Such a therapy would have applications in the treatment of a variety of genetic diseases, including cancer. However, despite its wide applicability, the technique is limited b...

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Bibliographic Details
Main Authors: Rūta Palepšienė, Martynas Maciulevičius, Paulius Ruzgys, Baltramiejus Jakštys, Saulius Šatkauskas
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Applied Sciences
Subjects:
calcium
electroporation
gene electrotransfer
cell death
electrotransfection
Online Access:https://www.mdpi.com/2076-3417/13/3/1983

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