Metabolic Profiling and Quantitative Analysis of Cerebrospinal Fluid Using Gas Chromatography–Mass Spectrometry: Current Methods and Future Perspectives

Metabolic Profiling and Quantitative Analysis of Cerebrospinal Fluid Using Gas Chromatography–Mass Spectrometry: Current Methods and Future Perspectives

Cerebrospinal fluid is a key biological fluid for the investigation of new potential biomarkers of central nervous system diseases. Gas chromatography coupled to mass-selective detectors can be used for this investigation at the stages of metabolic profiling and method development. Different sample...

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Bibliographic Details
Main Authors: Alisa Pautova, Natalia Burnakova, Alexander Revelsky
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
metabolomics
targeted analysis
nontargeted analysis
sample preparation
derivatization
validation
Online Access:https://www.mdpi.com/1420-3049/26/12/3597

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