Long-term postoperative pneumonia in elderly patients with early gastric cancer
Abstract Background Pneumonia is a major cause of death in the elderly population. Considering body weight loss, muscle loss, and reflux after gastrectomy, elderly patients are considered to be at very high risk for pneumonia, which could decrease overall survival because early gastric cancer is mos...
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| Format: | Article |
| Language: | English |
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BMC
2022-06-01
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| Series: | BMC Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12893-022-01670-4 |
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| author | Ayako Kamiya Tsutomu Hayashi Ryota Sakon Kenichi Ishizu Takeyuki Wada Sho Otsuki Yukinori Yamagata Hitoshi Katai Takaki Yoshikawa |
| author_facet | Ayako Kamiya Tsutomu Hayashi Ryota Sakon Kenichi Ishizu Takeyuki Wada Sho Otsuki Yukinori Yamagata Hitoshi Katai Takaki Yoshikawa |
| author_sort | Ayako Kamiya |
| collection | DOAJ |
| description | Abstract Background Pneumonia is a major cause of death in the elderly population. Considering body weight loss, muscle loss, and reflux after gastrectomy, elderly patients are considered to be at very high risk for pneumonia, which could decrease overall survival because early gastric cancer is mostly curable only by surgery. We aimed to clarify the incidence of pneumonia in the long-term period after gastrectomy in elderly patients who were diagnosed with early gastric cancer and its risk factors. Methods We retrospectively examined patients of > 75 years of age who underwent R0 gastrectomy for gastric cancer and who were diagnosed with T1 disease at National Cancer Center Hospital between 2005 and 2012. Long-term postoperative pneumonia was diagnosed by chest computed tomography every year until 2 years after surgery. The presence of preoperative sarcopenia was assessed using preoperative L3 skeletal muscle index. Results 167 patients were included in this study. Long-term postoperative pneumonia was observed in 44 (26%) patients. Of the 44 people diagnosed with long-term postoperative pneumonia, 33 were diagnosed in the 1st year and 11 in the 2nd year. 117 patients (70%) were diagnosed with sarcopenia which was significantly frequently found in the patients who developed long-term postoperative pneumonia (91%) than those without (63%). Preoperative sarcopenia was the only independent risk factor in multivariate analysis. Type of gastrectomy was not a significant risk factor. Conclusions Long-term postoperative pneumonia was frequently observed in the elderly patients. Preoperative sarcopenia was associated with long-term postoperative pneumonia in elderly patients who underwent curative surgery for gastric cancer. After gastrectomy, long-term special care would be required for elderly patients, especially with sarcopenia. |
| first_indexed | 2024-04-12T15:36:22Z |
| format | Article |
| id | doaj.art-22c829be895b4ff69d3909829e38706a |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-04-12T15:36:22Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-22c829be895b4ff69d3909829e38706a2022-12-22T03:26:56ZengBMCBMC Surgery1471-24822022-06-012211810.1186/s12893-022-01670-4Long-term postoperative pneumonia in elderly patients with early gastric cancerAyako Kamiya0Tsutomu Hayashi1Ryota Sakon2Kenichi Ishizu3Takeyuki Wada4Sho Otsuki5Yukinori Yamagata6Hitoshi Katai7Takaki Yoshikawa8Department of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalDepartment of Gastric Surgery, National Cancer Center HospitalAbstract Background Pneumonia is a major cause of death in the elderly population. Considering body weight loss, muscle loss, and reflux after gastrectomy, elderly patients are considered to be at very high risk for pneumonia, which could decrease overall survival because early gastric cancer is mostly curable only by surgery. We aimed to clarify the incidence of pneumonia in the long-term period after gastrectomy in elderly patients who were diagnosed with early gastric cancer and its risk factors. Methods We retrospectively examined patients of > 75 years of age who underwent R0 gastrectomy for gastric cancer and who were diagnosed with T1 disease at National Cancer Center Hospital between 2005 and 2012. Long-term postoperative pneumonia was diagnosed by chest computed tomography every year until 2 years after surgery. The presence of preoperative sarcopenia was assessed using preoperative L3 skeletal muscle index. Results 167 patients were included in this study. Long-term postoperative pneumonia was observed in 44 (26%) patients. Of the 44 people diagnosed with long-term postoperative pneumonia, 33 were diagnosed in the 1st year and 11 in the 2nd year. 117 patients (70%) were diagnosed with sarcopenia which was significantly frequently found in the patients who developed long-term postoperative pneumonia (91%) than those without (63%). Preoperative sarcopenia was the only independent risk factor in multivariate analysis. Type of gastrectomy was not a significant risk factor. Conclusions Long-term postoperative pneumonia was frequently observed in the elderly patients. Preoperative sarcopenia was associated with long-term postoperative pneumonia in elderly patients who underwent curative surgery for gastric cancer. After gastrectomy, long-term special care would be required for elderly patients, especially with sarcopenia.https://doi.org/10.1186/s12893-022-01670-4PneumoniaGastrectomyElderly patientsSarcopenia |
| spellingShingle | Ayako Kamiya Tsutomu Hayashi Ryota Sakon Kenichi Ishizu Takeyuki Wada Sho Otsuki Yukinori Yamagata Hitoshi Katai Takaki Yoshikawa Long-term postoperative pneumonia in elderly patients with early gastric cancer BMC Surgery Pneumonia Gastrectomy Elderly patients Sarcopenia |
| title | Long-term postoperative pneumonia in elderly patients with early gastric cancer |
| title_full | Long-term postoperative pneumonia in elderly patients with early gastric cancer |
| title_fullStr | Long-term postoperative pneumonia in elderly patients with early gastric cancer |
| title_full_unstemmed | Long-term postoperative pneumonia in elderly patients with early gastric cancer |
| title_short | Long-term postoperative pneumonia in elderly patients with early gastric cancer |
| title_sort | long term postoperative pneumonia in elderly patients with early gastric cancer |
| topic | Pneumonia Gastrectomy Elderly patients Sarcopenia |
| url | https://doi.org/10.1186/s12893-022-01670-4 |
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