TrkB phosphorylation in serum extracellular vesicles correlates with cognitive function enhanced by ergothioneine in humans
Abstract Oral administration of the food-derived antioxidant amino acid ergothioneine (ERGO) results in its efficient distribution in the brain and enhances cognitive function. However, effect of ERGO deficiency on cognitive impairment and the underlying mechanisms remain unknown. We revealed that c...
Main Authors: | Takahiro Ishimoto, Reiya Yamashita, Ruri Matsumoto, Satoshi Matsumoto, Yusuke Matsuo, Shunsuke Nakao, Yusuke Masuo, Makoto Suzuki, Yukio Kato |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
|
Series: | npj Science of Food |
Online Access: | https://doi.org/10.1038/s41538-024-00250-5 |
Similar Items
-
Organic cation transporter-mediated ergothioneine uptake in mouse neural progenitor cells suppresses proliferation and promotes differentiation into neurons.
by: Takahiro Ishimoto, et al.
Published: (2014-01-01) -
Food-derived antioxidant ergothioneine improves sleep difficulties in humans
by: Makoto Katsube, et al.
Published: (2022-08-01) -
Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists
by: Piotr Pankiewicz, et al.
Published: (2021-07-01) -
Cloning of a non-catalytic form of human trkB and distribution of messenger RNA for trkB in human brain.
by: Allen, S, et al.
Published: (1994) -
5-HT7 receptor activation promotes an increase in TrkB receptor expression and phosphorylation
by: Anshula eSamarajeewa, et al.
Published: (2014-11-01)