Comprehensive characterization of patient-derived xenograft models of pediatric leukemia

Comprehensive characterization of patient-derived xenograft models of pediatric leukemia

Summary: Patient-derived xenografts (PDX) remain valuable models for understanding the biology and for developing novel therapeutics. To expand current PDX models of childhood leukemia, we have developed new PDX models from Hispanic patients, a subgroup with a poorer overall outcome. Of 117 primary...

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Bibliographic Details
Main Authors: Anna Rogojina, Laura J. Klesse, Erin Butler, Jiwoong Kim, He Zhang, Xue Xiao, Lei Guo, Qinbo Zhou, Taylor Hartshorne, Dawn Garcia, Korri Weldon, Trevor Holland, Abhik Bandyopadhyay, Luz Perez Prado, Shidan Wang, Donghan M. Yang, Anne-Marie Langevan, Yi Zou, Allison C. Grimes, Chatchawin Assanasen, Vinod Gidvani-Diaz, Siyuan Zheng, Zhao Lai, Yidong Chen, Yang Xie, Gail E. Tomlinson, Stephen X. Skapek, Raushan T. Kurmasheva, Peter J. Houghton, Lin Xu
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Cancer
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223022484

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http://www.sciencedirect.com/science/article/pii/S2589004223022484

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