CRISPR-based genome editing in primary human pancreatic islet cells
The editing of primary human islets could provide insight into diabetes pathogenesis. Here the authors use CRISPR-Cas9 to target regulatory elements associated with T2D susceptibility.
Bibliographic Details
| Main Authors: |
Romina J. Bevacqua,
Xiaoqing Dai,
Jonathan Y. Lam,
Xueying Gu,
Mollie S. H. Friedlander,
Krissie Tellez,
Irene Miguel-Escalada,
Silvia Bonàs-Guarch,
Goutham Atla,
Weichen Zhao,
Seung Hyun Kim,
Antonia A. Dominguez,
Lei S. Qi,
Jorge Ferrer,
Patrick E. MacDonald,
Seung K. Kim |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2021-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-021-22651-w
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