Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI
Background: Metastatic osteosarcoma with direct cardiac involvement is an exceptionally rare finding. Reliable detection of cardiac metastases is known to be crucial for patients therapy and prognosis. Case Summary: In a 10-year-old boy affected by osteosarcoma of the left femur, a baseline Fluorine...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-06-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320300996 |
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| author | Verena Linder, MD Torsten Fritscher, MD Matthias Hammon, MD Michael Schroth, MD Wolfgang Schmidt, MD Michael Uder, MD Oliver Rompel, MD |
| author_facet | Verena Linder, MD Torsten Fritscher, MD Matthias Hammon, MD Michael Schroth, MD Wolfgang Schmidt, MD Michael Uder, MD Oliver Rompel, MD |
| author_sort | Verena Linder, MD |
| collection | DOAJ |
| description | Background: Metastatic osteosarcoma with direct cardiac involvement is an exceptionally rare finding. Reliable detection of cardiac metastases is known to be crucial for patients therapy and prognosis. Case Summary: In a 10-year-old boy affected by osteosarcoma of the left femur, a baseline Fluorine-18-fluorodeoxy-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) was performed to assess the full extent of disease. Whole-body scan detected numerous bone metastases together with a single pulmonary metastasis. Moreover, increased tracer uptake was observed in the intracavitary right cardiac ventricle in the position of a subtle spot of calcification. Because of nondetectability of a cavitary lesion on echocardiography, cardiac magnetic resonance imaging (CMRI) examination was performed to evaluate cardiac 18F-FDG PET/CT finding. CMRI revealed a small nodule in the right ventricle attached to the trabeculae, highly suspicious of a direct cardiac metastasis. After 4 cycles of chemotherapy, complete regression of tracer uptake of the lesion was observed on a follow-up 18F-FDG PET/CT scan. Conclusion: CMRI is able to detect even small, clinically asymptomatic cardiac metastases in young patients affected by osteosarcoma. |
| first_indexed | 2024-12-13T11:58:36Z |
| format | Article |
| id | doaj.art-22e06416c1b24ea9a663367d0ea95aec |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-13T11:58:36Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-22e06416c1b24ea9a663367d0ea95aec2022-12-21T23:47:08ZengElsevierRadiology Case Reports1930-04332020-06-01156761764Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRIVerena Linder, MD0Torsten Fritscher, MD1Matthias Hammon, MD2Michael Schroth, MD3Wolfgang Schmidt, MD4Michael Uder, MD5Oliver Rompel, MD6Department of Pediatrics and Adolescent Medicine, Cnopf Children's Hospital, St. Johannis Mühlgasse 19, Nürnberg 90419, Germany; Corresponding author.Department of Radiology and Nuclear Medicine, Paracelsus Medical University, Nürnberg, GermanyDepartment of Radiology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, GermanyDepartment of Pediatrics and Adolescent Medicine, Cnopf Children's Hospital, St. Johannis Mühlgasse 19, Nürnberg 90419, GermanyDepartment of Pediatrics and Adolescent Medicine, Cnopf Children's Hospital, St. Johannis Mühlgasse 19, Nürnberg 90419, GermanyDepartment of Radiology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, GermanyDepartment of Radiology, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, GermanyBackground: Metastatic osteosarcoma with direct cardiac involvement is an exceptionally rare finding. Reliable detection of cardiac metastases is known to be crucial for patients therapy and prognosis. Case Summary: In a 10-year-old boy affected by osteosarcoma of the left femur, a baseline Fluorine-18-fluorodeoxy-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) was performed to assess the full extent of disease. Whole-body scan detected numerous bone metastases together with a single pulmonary metastasis. Moreover, increased tracer uptake was observed in the intracavitary right cardiac ventricle in the position of a subtle spot of calcification. Because of nondetectability of a cavitary lesion on echocardiography, cardiac magnetic resonance imaging (CMRI) examination was performed to evaluate cardiac 18F-FDG PET/CT finding. CMRI revealed a small nodule in the right ventricle attached to the trabeculae, highly suspicious of a direct cardiac metastasis. After 4 cycles of chemotherapy, complete regression of tracer uptake of the lesion was observed on a follow-up 18F-FDG PET/CT scan. Conclusion: CMRI is able to detect even small, clinically asymptomatic cardiac metastases in young patients affected by osteosarcoma.http://www.sciencedirect.com/science/article/pii/S1930043320300996CMRIDirect cardiac metastasisOsteosarcoma |
| spellingShingle | Verena Linder, MD Torsten Fritscher, MD Matthias Hammon, MD Michael Schroth, MD Wolfgang Schmidt, MD Michael Uder, MD Oliver Rompel, MD Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI Radiology Case Reports CMRI Direct cardiac metastasis Osteosarcoma |
| title | Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI |
| title_full | Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI |
| title_fullStr | Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI |
| title_full_unstemmed | Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI |
| title_short | Small direct right ventricular cardiac metastasis of osteosarcoma in a 10-year-old boy affirmed by cardiac MRI |
| title_sort | small direct right ventricular cardiac metastasis of osteosarcoma in a 10 year old boy affirmed by cardiac mri |
| topic | CMRI Direct cardiac metastasis Osteosarcoma |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320300996 |
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