The solubility product extends the buffering concept to heterotypic biomolecular condensates
Biomolecular condensates are formed by liquid-liquid phase separation (LLPS) of multivalent molecules. LLPS from a single ("homotypic") constituent is governed by buffering: above a threshold, free monomer concentration is clamped, with all added molecules entering the condensed phase. How...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-07-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/67176 |