The solubility product extends the buffering concept to heterotypic biomolecular condensates
Biomolecular condensates are formed by liquid-liquid phase separation (LLPS) of multivalent molecules. LLPS from a single ("homotypic") constituent is governed by buffering: above a threshold, free monomer concentration is clamped, with all added molecules entering the condensed phase. How...
Main Authors: | Aniruddha Chattaraj, Michael L Blinov, Leslie M Loew |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-07-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/67176 |
Similar Items
-
Landscape of biomolecular condensates in heat stress responses
by: Violeta Londoño Vélez, et al.
Published: (2022-10-01) -
Liquid Biomolecular Condensates and Viral Lifecycles: Review and Perspectives
by: Temitope Akhigbe Etibor, et al.
Published: (2021-02-01) -
Biomolecular condensates: insights into early and late steps of the HIV-1 replication cycle
by: Francesca Di Nunzio, et al.
Published: (2023-04-01) -
Molecular Organization and Regulation of the Mammalian Synapse by the Post-Translational Modification SUMOylation
by: Isabel Chato-Astrain, et al.
Published: (2024-02-01) -
Biomolecular condensates: Formation mechanisms, biological functions, and therapeutic targets
by: Xin Niu, et al.
Published: (2023-04-01)