The solubility product extends the buffering concept to heterotypic biomolecular condensates

Biomolecular condensates are formed by liquid-liquid phase separation (LLPS) of multivalent molecules. LLPS from a single ("homotypic") constituent is governed by buffering: above a threshold, free monomer concentration is clamped, with all added molecules entering the condensed phase. How...

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Bibliographic Details
Main Authors: Aniruddha Chattaraj, Michael L Blinov, Leslie M Loew
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/67176

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