Structure-activity relationships of constrained phenylethylamine ligands for the serotonin 5-HT2 receptors.
Serotonergic ligands have proven effective drugs in the treatment of migraine, pain, obesity, and a wide range of psychiatric and neurological disorders. There is a clinical need for more highly 5-HT2 receptor subtype-selective ligands and the most attention has been given to the phenethylamine clas...
Main Authors: | Vignir Isberg, James Paine, Sebastian Leth-Petersen, Jesper L Kristensen, David E Gloriam |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3820707?pdf=render |
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