HLA alleles associated with asparaginase hypersensitivity in Chinese children

HLA alleles associated with asparaginase hypersensitivity in Chinese children

Abstract Asparaginase is an important drug to treat childhood haematological malignancies. Data on the association between human leukocyte antigens (HLA) and asparaginase hypersensitivity among Chinese are lacking. We conducted a retrospective study to identify HLA alleles associated with asparagina...

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Bibliographic Details
Main Authors: Gilbert T. Chua, Jaime S. Rosa Duque, Daniel Ka Leung Cheuk, Alex Wing Kwan Leung, Wilfred Hing Sang Wong, Anthony Pak Yin Liu, Pamela P. W. Lee, Shau Yin Ha, Alan Kwok Shing Chiang, Marco Hok Kung Ho, Wai Keung Chu, Yuk Sing Chan, Chun Wing Luk, Alvin Siu Cheung Ling, Mike Yat Wah Kwan, Oscar Kuen Fong Yiu, Ian Chi Kei Wong, Yu Lung Lau, Chi Kong Li, Wing Hang Leung, Godfrey Chi Fung Chan, Patrick Ip, Janette Kwok
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Journal of Hematology & Oncology
Subjects:
Human leukocyte antigens
Asparaginase
Hypersensitivity
Allergy
Chinese
Children
Online Access:https://doi.org/10.1186/s13045-021-01201-3

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