MicroRNA-494-3p prevents liver fibrosis and attenuates hepatic stellate cell activation by inhibiting proliferation and inducing apoptosis through targeting TRAF3

MicroRNA-494-3p prevents liver fibrosis and attenuates hepatic stellate cell activation by inhibiting proliferation and inducing apoptosis through targeting TRAF3

Introduction and objectives: Alcoholic hepatitis (AH) is characterized by high morbidity and mortality. MicroRNA-494-3p is possibly involved in the regulation of cancers, but its role in AH has been rarely studied. Materials and methods: AH mice model and primarily cultured mice hepatic stellate cel...

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Bibliographic Details
Main Authors: Hualong Li, Lei Zhang, Nan Cai, Bing Zhang, Shaomei Sun
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Annals of Hepatology
Subjects:
Alcoholic hepatitis
Hepatic stellate cell
miR-494-3p
TNF receptor-associated factor 3
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268121000041

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