Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue...
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Format: | Article |
Language: | English |
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Nature Portfolio
2020-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-15283-z |
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author | Sabra I. Djomehri Maria E. Gonzalez Felipe da Veiga Leprevost Shilpa R. Tekula Hui-Yin Chang Marissa J. White Ashley Cimino-Mathews Boris Burman Venkatesha Basrur Pedram Argani Alexey I. Nesvizhskii Celina G. Kleer |
author_facet | Sabra I. Djomehri Maria E. Gonzalez Felipe da Veiga Leprevost Shilpa R. Tekula Hui-Yin Chang Marissa J. White Ashley Cimino-Mathews Boris Burman Venkatesha Basrur Pedram Argani Alexey I. Nesvizhskii Celina G. Kleer |
author_sort | Sabra I. Djomehri |
collection | DOAJ |
description | Metaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue. |
first_indexed | 2024-12-17T09:41:54Z |
format | Article |
id | doaj.art-22ef73a0f75440e0a22ac00ea2373d42 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-17T09:41:54Z |
publishDate | 2020-04-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-22ef73a0f75440e0a22ac00ea2373d422022-12-21T21:53:52ZengNature PortfolioNature Communications2041-17232020-04-0111111510.1038/s41467-020-15283-zQuantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumorsSabra I. Djomehri0Maria E. Gonzalez1Felipe da Veiga Leprevost2Shilpa R. Tekula3Hui-Yin Chang4Marissa J. White5Ashley Cimino-Mathews6Boris Burman7Venkatesha Basrur8Pedram Argani9Alexey I. Nesvizhskii10Celina G. Kleer11Department of Pathology, University of Michigan Medical SchoolDepartment of Pathology, University of Michigan Medical SchoolDepartment of Pathology, University of Michigan Medical SchoolDepartment of Pathology, University of Michigan Medical SchoolDepartment of Pathology, University of Michigan Medical SchoolDepartment of Pathology, Johns Hopkins UniversityDepartment of Pathology, Johns Hopkins UniversityDepartment of Pathology, University of Michigan Medical SchoolDepartment of Pathology, University of Michigan Medical SchoolDepartment of Pathology, Johns Hopkins UniversityDepartment of Pathology, University of Michigan Medical SchoolDepartment of Pathology, University of Michigan Medical SchoolMetaplastic breast carcinoma (MBC) is among the most aggressive subtypes of triple-negative breast cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize the protein signatures of human MBC tissue samples and their relationship to TNBC and normal breast tissue.https://doi.org/10.1038/s41467-020-15283-z |
spellingShingle | Sabra I. Djomehri Maria E. Gonzalez Felipe da Veiga Leprevost Shilpa R. Tekula Hui-Yin Chang Marissa J. White Ashley Cimino-Mathews Boris Burman Venkatesha Basrur Pedram Argani Alexey I. Nesvizhskii Celina G. Kleer Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors Nature Communications |
title | Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors |
title_full | Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors |
title_fullStr | Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors |
title_full_unstemmed | Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors |
title_short | Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors |
title_sort | quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple negative tumors |
url | https://doi.org/10.1038/s41467-020-15283-z |
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