Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised Study
Background: Pnuemoperitonium in laparoscopy is associated with cardiorespiratory changes. Combination of epidural with General anaesthesia (GA) will offer benefit of hemodynamic control and perioperative analgesia. We aimed to study the efficacy of Combined Epidural- General Anaesthesia (CEGA) with...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-08-01
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| Series: | Archives of Anesthesia and Critical Care |
| Subjects: | |
| Online Access: | https://aacc.tums.ac.ir/index.php/aacc/article/view/685 |
| _version_ | 1797359879391805440 |
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| author | Nethra H Nanjundaswamy Sudheesh Kannan Vijaykumar H Narayanappa Saraswathi Nagappa Sandya Kalappa |
| author_facet | Nethra H Nanjundaswamy Sudheesh Kannan Vijaykumar H Narayanappa Saraswathi Nagappa Sandya Kalappa |
| author_sort | Nethra H Nanjundaswamy |
| collection | DOAJ |
| description |
Background: Pnuemoperitonium in laparoscopy is associated with cardiorespiratory changes. Combination of epidural with General anaesthesia (GA) will offer benefit of hemodynamic control and perioperative analgesia. We aimed to study the efficacy of Combined Epidural- General Anaesthesia (CEGA) with pre-emptive activation over general anaesthesia in laparoscopic cholecystectomies.
Methods: In this prospective double blind –randomised study, 90 surgical inpatients were studied in two study groups. Group GE-(n=45) received Lumbar Epidural analgesia with ropivacaine 0.2% along with GA and Group G (n=45) received only GA. Heart rate (HR), Mean arterial Pressure (MAP), systolic blood pressure (SBP), diastolic blood pressure (DBP), Capnogram (ETCO2), saturation (spo2), VAS score, Ramsay sedation score, requirement of propofol, muscle relaxants and analgesics were studied.
Results: Statistical analysis was carried out with SPSS version 20. Statistical value of p<0.05 was considered significant. We noted significant difference in MAP, SBP, DBP, muscle relaxants, Propofol, Fentanyl and lesser pain scores in Group GE than Group G i.e (p<0.001).
Conclusion: Combination of epidural and general anaesthesia technique with pre emptive activation has the benefit of better control of hemodynamics .It reduced requirements of analgesics and anaesthetic drugs and had faster recovery with less post operative pain in laparoscopic cholecystectomies.
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| first_indexed | 2024-03-08T15:30:10Z |
| format | Article |
| id | doaj.art-22f0436669e64783a75e2145ca79d51e |
| institution | Directory Open Access Journal |
| issn | 2423-5849 |
| language | English |
| last_indexed | 2024-03-08T15:30:10Z |
| publishDate | 2023-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Archives of Anesthesia and Critical Care |
| spelling | doaj.art-22f0436669e64783a75e2145ca79d51e2024-01-10T05:56:07ZengTehran University of Medical SciencesArchives of Anesthesia and Critical Care2423-58492023-08-019Supp. 210.18502/aacc.v9i6.14447Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised StudyNethra H Nanjundaswamy0Sudheesh Kannan1Vijaykumar H Narayanappa2Saraswathi Nagappa3Sandya Kalappa4Bangalore Medical College and Research Institute, Departmentof Anaesthesiology,Victoria Hospital, Bangalore,India.Bangalore Medical College and Research Institute, Departmentof Anaesthesiology,Victoria Hospital, Bangalore,India.Bangalore Medical College and Research Institute, Departmentof Anaesthesiology, Victoria Hospital, Bangalore, India.Bangalore Medical College and Research Institute, Departmentof Anaesthesiology, Victoria Hospital, Bangalore, India.Bangalore Medical College and Research Institute, Departmentof Anaesthesiology, Victoria Hospital, Bangalore, India. Background: Pnuemoperitonium in laparoscopy is associated with cardiorespiratory changes. Combination of epidural with General anaesthesia (GA) will offer benefit of hemodynamic control and perioperative analgesia. We aimed to study the efficacy of Combined Epidural- General Anaesthesia (CEGA) with pre-emptive activation over general anaesthesia in laparoscopic cholecystectomies. Methods: In this prospective double blind –randomised study, 90 surgical inpatients were studied in two study groups. Group GE-(n=45) received Lumbar Epidural analgesia with ropivacaine 0.2% along with GA and Group G (n=45) received only GA. Heart rate (HR), Mean arterial Pressure (MAP), systolic blood pressure (SBP), diastolic blood pressure (DBP), Capnogram (ETCO2), saturation (spo2), VAS score, Ramsay sedation score, requirement of propofol, muscle relaxants and analgesics were studied. Results: Statistical analysis was carried out with SPSS version 20. Statistical value of p<0.05 was considered significant. We noted significant difference in MAP, SBP, DBP, muscle relaxants, Propofol, Fentanyl and lesser pain scores in Group GE than Group G i.e (p<0.001). Conclusion: Combination of epidural and general anaesthesia technique with pre emptive activation has the benefit of better control of hemodynamics .It reduced requirements of analgesics and anaesthetic drugs and had faster recovery with less post operative pain in laparoscopic cholecystectomies. https://aacc.tums.ac.ir/index.php/aacc/article/view/685EpiduralGeneral anaesthesiaLaparoscopyCEGAEfficacyCholecystectomy |
| spellingShingle | Nethra H Nanjundaswamy Sudheesh Kannan Vijaykumar H Narayanappa Saraswathi Nagappa Sandya Kalappa Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised Study Archives of Anesthesia and Critical Care Epidural General anaesthesia Laparoscopy CEGA Efficacy Cholecystectomy |
| title | Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised Study |
| title_full | Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised Study |
| title_fullStr | Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised Study |
| title_full_unstemmed | Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised Study |
| title_short | Efficacy of Combined Epidural-General Anaesthesia [CEGA] in Attenuating Hemodynamic Responses to Pneumoperitoneum in Laparoscopic Cholecystectomies: A Prospective Randomised Study |
| title_sort | efficacy of combined epidural general anaesthesia cega in attenuating hemodynamic responses to pneumoperitoneum in laparoscopic cholecystectomies a prospective randomised study |
| topic | Epidural General anaesthesia Laparoscopy CEGA Efficacy Cholecystectomy |
| url | https://aacc.tums.ac.ir/index.php/aacc/article/view/685 |
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