Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion

Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion

Abstract Background As important players in cell-to-cell communication, exosomes (exo) are believed to play a similar role in promoting fracture healing. This study investigated whether exosomes derived from bone marrow mesenchymal stem cells (BMMSC-Exos) could improve fracture healing of nonunion....

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Bibliographic Details
Main Authors: Lu Zhang, Guangjun Jiao, Shanwu Ren, Xiaoqian Zhang, Ci Li, Wenliang Wu, Hongliang Wang, Haichun Liu, Hongming Zhou, Yunzhen Chen
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Exosomes
Nonunion
Osteogenesis
Angiogenesis
Online Access:https://doi.org/10.1186/s13287-020-1562-9

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