CDK5RAP2 is a Wnt target gene and promotes stemness and progression of oral squamous cell carcinoma

CDK5RAP2 is a Wnt target gene and promotes stemness and progression of oral squamous cell carcinoma

Abstract In oral squamous cell carcinoma (OSCC), a highly aggressive and frequently lethal malignancy, the role and action mechanism of the microtubule regulatory protein CDK5RAP2 have not been fully understood. Here, we show that CDK5RAP2 is highly expressed in OSCC and its expression correlates wi...

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Bibliographic Details
Main Authors: Yuehong Shen, Yuling Chen, Yuntao Lin, Yicun Li, Pengfei Liu, Biru Zhang, Yufan Wang, King-Chi Chan, Nai-Ki Mak, Michael Kahn, Robert Z. Qi, Hongyu Yang
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05652-z

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