Regulation of Inflammation-Mediated Endothelial to Mesenchymal Transition with Echinochrome a for Improving Myocardial Dysfunction

Regulation of Inflammation-Mediated Endothelial to Mesenchymal Transition with Echinochrome a for Improving Myocardial Dysfunction

Endothelial–mesenchymal transition (EndMT) is a process by which endothelial cells (ECs) transition into mesenchymal cells (e.g., myofibroblasts and smooth muscle cells) and induce fibrosis of cells/tissues, due to ischemic conditions in the heart. Previously, we reported that echinochrome A (EchA)...

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Bibliographic Details
Main Authors: Byeong-Wook Song, Sejin Kim, Ran Kim, Seongtae Jeong, Hanbyeol Moon, Hojin Kim, Elena A. Vasileva, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Min Young Lee, Jongmin Kim, Hyoung Kyu Kim, Jin Han, Woochul Chang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Marine Drugs
Subjects:
endothelial–mesenchymal transition
echinochrome A
myocardial infarction
cardiac fibrosis
Online Access:https://www.mdpi.com/1660-3397/20/12/756

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