Separation and structural elucidation of a novel vardenafil analogue as an adulterant in a natural health care dietary supplement

Separation and structural elucidation of a novel vardenafil analogue as an adulterant in a natural health care dietary supplement

A novel vardenafil analogue was identified in dietary supplement as an adulterant in herbal formulations. The structure of this analogue was elucidated using HRMS, NMR after extraction from the pulverized powder. It was named morphardenafil as a morpholine ring has replaced the N-ethyl piperazine ri...

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Bibliographic Details
Main Authors: Chunzheng Li, Xinzheng Wang, Shengming Wu, Junqing Zhao, Junjian Fang, Hui Li, Yingjie Zhu, Kang Zhang, Jing Peng, Jie Mao, Weihua Li, Kun He, Na Wang, Fangting Dong
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Heliyon
Subjects:
Vardenafil analogue
PDE-5 inhibitor
Dietary supplement
Adulterants
Morpholine ring
HRMS
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023026257

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http://www.sciencedirect.com/science/article/pii/S2405844023026257

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