Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases.
<h4>Objective</h4>To analyze the relationship between regular physical activity, as assessed by accelerometer and 7-day physical activity recall (PAR), and plasma fibrinogen concentrations.<h4>Methods</h4>A cross-sectional study in a previously established cohort of healthy s...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24498413/?tool=EBI |
| _version_ | 1828975807677071360 |
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| author | Manuel A Gomez-Marcos José I Recio-Rodríguez Maria C Patino-Alonso Vicente Martinez-Vizcaino Carme Martin-Borras Aventina de-la-Cal-Dela-Fuente Ines Sauras-Llera Alvaro Sanchez-Perez Cristina Agudo-Conde Luis García-Ortiz EVIDENT Study Investigators |
| author_facet | Manuel A Gomez-Marcos José I Recio-Rodríguez Maria C Patino-Alonso Vicente Martinez-Vizcaino Carme Martin-Borras Aventina de-la-Cal-Dela-Fuente Ines Sauras-Llera Alvaro Sanchez-Perez Cristina Agudo-Conde Luis García-Ortiz EVIDENT Study Investigators |
| author_sort | Manuel A Gomez-Marcos |
| collection | DOAJ |
| description | <h4>Objective</h4>To analyze the relationship between regular physical activity, as assessed by accelerometer and 7-day physical activity recall (PAR), and plasma fibrinogen concentrations.<h4>Methods</h4>A cross-sectional study in a previously established cohort of healthy subjects was performed. This study analyzed 1284 subjects who were included in the EVIDENT study (mean age 55.0±13.6 years; 60.90% women). Fibrinogen concentrations were measured in blood plasma. Physical activity was assessed with a 7-day PAR (metabolic equivalents (METs)/hour/week) and GT3X ActiGraph accelerometer (counts/minute) for 7 days.<h4>Results</h4>Physical exercise, which was evaluated with both an accelerometer (Median: 237.28 counts/minute) and 7-day PAR (Median: 8 METs/hour/week). Physical activity was negatively correlated with plasma fibrinogen concentrations, which was evaluated by counts/min (r = -0.100; p<0.001) and METs/hour/week (r = -0.162; p<0.001). In a multiple linear regression analysis, fibrinogen concentrations of the subjects who performed more physical activity (third tertile of count/minute and METs/hour/week) respect to subjects who performed less (first tertile), maintained statistical significance after adjustments for age and others confounders (β = -0.03; p = 0.046 and β = -0.06; p<0.001, respectively).<h4>Conclusions</h4>Physical activity, as assessed by accelerometer and 7-day PAR, was negatively associated with plasma fibrinogen concentrations. This relation is maintained in subjects who performed more exercise even after adjusting for age and other confounders. |
| first_indexed | 2024-12-14T14:26:20Z |
| format | Article |
| id | doaj.art-22fdd652cda94ceead96f003bbd66384 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-14T14:26:20Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-22fdd652cda94ceead96f003bbd663842022-12-21T22:57:56ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0192e8795410.1371/journal.pone.0087954Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases.Manuel A Gomez-MarcosJosé I Recio-RodríguezMaria C Patino-AlonsoVicente Martinez-VizcainoCarme Martin-BorrasAventina de-la-Cal-Dela-FuenteInes Sauras-LleraAlvaro Sanchez-PerezCristina Agudo-CondeLuis García-OrtizEVIDENT Study Investigators<h4>Objective</h4>To analyze the relationship between regular physical activity, as assessed by accelerometer and 7-day physical activity recall (PAR), and plasma fibrinogen concentrations.<h4>Methods</h4>A cross-sectional study in a previously established cohort of healthy subjects was performed. This study analyzed 1284 subjects who were included in the EVIDENT study (mean age 55.0±13.6 years; 60.90% women). Fibrinogen concentrations were measured in blood plasma. Physical activity was assessed with a 7-day PAR (metabolic equivalents (METs)/hour/week) and GT3X ActiGraph accelerometer (counts/minute) for 7 days.<h4>Results</h4>Physical exercise, which was evaluated with both an accelerometer (Median: 237.28 counts/minute) and 7-day PAR (Median: 8 METs/hour/week). Physical activity was negatively correlated with plasma fibrinogen concentrations, which was evaluated by counts/min (r = -0.100; p<0.001) and METs/hour/week (r = -0.162; p<0.001). In a multiple linear regression analysis, fibrinogen concentrations of the subjects who performed more physical activity (third tertile of count/minute and METs/hour/week) respect to subjects who performed less (first tertile), maintained statistical significance after adjustments for age and others confounders (β = -0.03; p = 0.046 and β = -0.06; p<0.001, respectively).<h4>Conclusions</h4>Physical activity, as assessed by accelerometer and 7-day PAR, was negatively associated with plasma fibrinogen concentrations. This relation is maintained in subjects who performed more exercise even after adjusting for age and other confounders.https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24498413/?tool=EBI |
| spellingShingle | Manuel A Gomez-Marcos José I Recio-Rodríguez Maria C Patino-Alonso Vicente Martinez-Vizcaino Carme Martin-Borras Aventina de-la-Cal-Dela-Fuente Ines Sauras-Llera Alvaro Sanchez-Perez Cristina Agudo-Conde Luis García-Ortiz EVIDENT Study Investigators Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases. PLoS ONE |
| title | Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases. |
| title_full | Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases. |
| title_fullStr | Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases. |
| title_full_unstemmed | Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases. |
| title_short | Relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases. |
| title_sort | relationship between physical activity and plasma fibrinogen concentrations in adults without chronic diseases |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24498413/?tool=EBI |
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