Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
Purpose: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. Design: Prospective noncomparative cohort study. Materials...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2009-01-01
|
| Series: | Oman Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ojoonline.org/article.asp?issn=0974-620X;year=2009;volume=2;issue=1;spage=23;epage=26;aulast=Mahdy |
| _version_ | 1818450956993429504 |
|---|---|
| author | Mohamed A. E. Soliman Mahdy Jagdish Bhatia |
| author_facet | Mohamed A. E. Soliman Mahdy Jagdish Bhatia |
| author_sort | Mohamed A. E. Soliman Mahdy |
| collection | DOAJ |
| description | Purpose: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed.
Design: Prospective noncomparative cohort study.
Materials and Methods: Forty-two eyes of 42 patients with grade I-III primary pterygium were included in the study. Pterygium excision was performed followed by superotemporal limbal stem cells and conjunctival autograft transplantation in all cases. Recurrence of pterygium and complications within a mean follow-up period of 18.26 months (10-28 months) was studied.
Results: Recurrence of pterygium occurred in two eyes (2/42; 4.75%). No significant complications were noted. Apart from re-operation in the two recurrent cases, no further surgical interventions were needed in any case.
Conclusions: Limbal stem cells and conjunctival autograft transplantation is a safe and effective technique for the treatment of different grades of pterygium. It is very useful in preventing pterygium recurrence, which is a major problem in pterygium surgery. |
| first_indexed | 2024-12-14T20:59:33Z |
| format | Article |
| id | doaj.art-230099c4910f4cb7a89dc056971b04fc |
| institution | Directory Open Access Journal |
| issn | 0974-620X |
| language | English |
| last_indexed | 2024-12-14T20:59:33Z |
| publishDate | 2009-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Oman Journal of Ophthalmology |
| spelling | doaj.art-230099c4910f4cb7a89dc056971b04fc2022-12-21T22:47:36ZengWolters Kluwer Medknow PublicationsOman Journal of Ophthalmology0974-620X2009-01-0121232610.4103/0974-620X.48418Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantationMohamed A. E. Soliman MahdyJagdish BhatiaPurpose: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. Design: Prospective noncomparative cohort study. Materials and Methods: Forty-two eyes of 42 patients with grade I-III primary pterygium were included in the study. Pterygium excision was performed followed by superotemporal limbal stem cells and conjunctival autograft transplantation in all cases. Recurrence of pterygium and complications within a mean follow-up period of 18.26 months (10-28 months) was studied. Results: Recurrence of pterygium occurred in two eyes (2/42; 4.75%). No significant complications were noted. Apart from re-operation in the two recurrent cases, no further surgical interventions were needed in any case. Conclusions: Limbal stem cells and conjunctival autograft transplantation is a safe and effective technique for the treatment of different grades of pterygium. It is very useful in preventing pterygium recurrence, which is a major problem in pterygium surgery.http://www.ojoonline.org/article.asp?issn=0974-620X;year=2009;volume=2;issue=1;spage=23;epage=26;aulast=MahdyPterygiumautograftexcisionstem cells |
| spellingShingle | Mohamed A. E. Soliman Mahdy Jagdish Bhatia Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation Oman Journal of Ophthalmology Pterygium autograft excision stem cells |
| title | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
| title_full | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
| title_fullStr | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
| title_full_unstemmed | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
| title_short | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
| title_sort | treatment of primary pterygium role of limbal stem cells and conjunctival autograft transplantation |
| topic | Pterygium autograft excision stem cells |
| url | http://www.ojoonline.org/article.asp?issn=0974-620X;year=2009;volume=2;issue=1;spage=23;epage=26;aulast=Mahdy |
| work_keys_str_mv | AT mohamedaesolimanmahdy treatmentofprimarypterygiumroleoflimbalstemcellsandconjunctivalautografttransplantation AT jagdishbhatia treatmentofprimarypterygiumroleoflimbalstemcellsandconjunctivalautografttransplantation |