Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patient

<p>Abstract</p> <p>We report on a case of autoimmune thyroiditis in a 6-month-old patient with cortico-resistant nephrotic syndrome. Normal serum levels of thyroid hormons and thyroid-stimulating hormone were detected with high titers of circulant antithyroid antibodies and a dysom...

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Main Authors: Urbano Flavia, Acquafredda Angelo, Aceto Gabriella, Penza Rosa, Cavallo Luciano
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Italian Journal of Pediatrics
Subjects:
Online Access:http://www.ijponline.net/content/38/1/57
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author Urbano Flavia
Acquafredda Angelo
Aceto Gabriella
Penza Rosa
Cavallo Luciano
author_facet Urbano Flavia
Acquafredda Angelo
Aceto Gabriella
Penza Rosa
Cavallo Luciano
author_sort Urbano Flavia
collection DOAJ
description <p>Abstract</p> <p>We report on a case of autoimmune thyroiditis in a 6-month-old patient with cortico-resistant nephrotic syndrome. Normal serum levels of thyroid hormons and thyroid-stimulating hormone were detected with high titers of circulant antithyroid antibodies and a dysomogeneous ultrasound appearance of the gland, typical of autoimmune thyroiditis. The research of maternal thyroid antibodies was negative. This is the first case of autoimmune thyroiditis found in such a young patient with pre-existing nephrotic syndrome ever described in literature. This association is random because nephrotic syndrome does not have an autoimmune pathogenesis and the genes involved in autoimmune thyroiditis are not related to those of nephrotic syndrome.</p>
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spelling doaj.art-23026148648740c287b04778ed0b87c52022-12-22T00:37:49ZengBMCItalian Journal of Pediatrics1720-84241824-72882012-10-013815710.1186/1824-7288-38-57Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patientUrbano FlaviaAcquafredda AngeloAceto GabriellaPenza RosaCavallo Luciano<p>Abstract</p> <p>We report on a case of autoimmune thyroiditis in a 6-month-old patient with cortico-resistant nephrotic syndrome. Normal serum levels of thyroid hormons and thyroid-stimulating hormone were detected with high titers of circulant antithyroid antibodies and a dysomogeneous ultrasound appearance of the gland, typical of autoimmune thyroiditis. The research of maternal thyroid antibodies was negative. This is the first case of autoimmune thyroiditis found in such a young patient with pre-existing nephrotic syndrome ever described in literature. This association is random because nephrotic syndrome does not have an autoimmune pathogenesis and the genes involved in autoimmune thyroiditis are not related to those of nephrotic syndrome.</p>http://www.ijponline.net/content/38/1/57Autoimmune thyroiditisNephrotic syndromeChildhood
spellingShingle Urbano Flavia
Acquafredda Angelo
Aceto Gabriella
Penza Rosa
Cavallo Luciano
Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patient
Italian Journal of Pediatrics
Autoimmune thyroiditis
Nephrotic syndrome
Childhood
title Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patient
title_full Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patient
title_fullStr Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patient
title_full_unstemmed Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patient
title_short Unusual pediatric co-morbility: autoimmune thyroiditis and cortico-resistant nephrotic syndrome in a 6-month-old Italian patient
title_sort unusual pediatric co morbility autoimmune thyroiditis and cortico resistant nephrotic syndrome in a 6 month old italian patient
topic Autoimmune thyroiditis
Nephrotic syndrome
Childhood
url http://www.ijponline.net/content/38/1/57
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