Gut microbiota in COVID-19: new insights from inside
ABSTRACTThe epidemic of coronavirus disease-19 (COVID-19) has grown to be a global health threat. Gastrointestinal symptoms are thought to be common clinical manifestations apart from a series of originally found respiratory symptoms. The human gut harbors trillions of microorganisms that are indisp...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Gut Microbes |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19490976.2023.2201157 |
| _version_ | 1797236631769448448 |
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| author | Bingqian Zhou Xiaoqi Pang Jingyi Wu Tianyu Liu Bangmao Wang Hailong Cao |
| author_facet | Bingqian Zhou Xiaoqi Pang Jingyi Wu Tianyu Liu Bangmao Wang Hailong Cao |
| author_sort | Bingqian Zhou |
| collection | DOAJ |
| description | ABSTRACTThe epidemic of coronavirus disease-19 (COVID-19) has grown to be a global health threat. Gastrointestinal symptoms are thought to be common clinical manifestations apart from a series of originally found respiratory symptoms. The human gut harbors trillions of microorganisms that are indispensable for complex physiological processes and homeostasis. Growing evidence demonstrate that gut microbiota alteration is associated with COVID-19 progress and severity, and post-COVID-19 syndrome, characterized by decrease of anti-inflammatory bacteria like Bifidobacterium and Faecalibacterium and enrichment of inflammation-associated microbiota including Streptococcus and Actinomyces. Therapeutic strategies such as diet, probiotics/prebiotics, herb, and fecal microbiota transplantation have shown positive effects on relieving clinical symptoms. In this article, we provide and summarize the recent evidence about the gut microbiota and their metabolites alterations during and after COVID-19 infection and focus on potential therapeutic strategies targeting gut microbiota. Understanding the connections between intestinal microbiota and COVID-19 would provide new insights into COVID-19 management in the future. |
| first_indexed | 2024-03-11T14:20:07Z |
| format | Article |
| id | doaj.art-2302d28fa1f9472690cda9bfeba4caba |
| institution | Directory Open Access Journal |
| issn | 1949-0976 1949-0984 |
| language | English |
| last_indexed | 2024-04-24T17:06:56Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Gut Microbes |
| spelling | doaj.art-2302d28fa1f9472690cda9bfeba4caba2024-03-28T22:38:20ZengTaylor & Francis GroupGut Microbes1949-09761949-09842023-12-0115110.1080/19490976.2023.2201157Gut microbiota in COVID-19: new insights from insideBingqian Zhou0Xiaoqi Pang1Jingyi Wu2Tianyu LiuBangmao WangHailong Cao3Department of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, ChinaDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, ChinaDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, ChinaDepartment of Gastroenterology and Hepatology, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases, Tianjin Key Laboratory of Digestive Diseases, Tianjin, ChinaABSTRACTThe epidemic of coronavirus disease-19 (COVID-19) has grown to be a global health threat. Gastrointestinal symptoms are thought to be common clinical manifestations apart from a series of originally found respiratory symptoms. The human gut harbors trillions of microorganisms that are indispensable for complex physiological processes and homeostasis. Growing evidence demonstrate that gut microbiota alteration is associated with COVID-19 progress and severity, and post-COVID-19 syndrome, characterized by decrease of anti-inflammatory bacteria like Bifidobacterium and Faecalibacterium and enrichment of inflammation-associated microbiota including Streptococcus and Actinomyces. Therapeutic strategies such as diet, probiotics/prebiotics, herb, and fecal microbiota transplantation have shown positive effects on relieving clinical symptoms. In this article, we provide and summarize the recent evidence about the gut microbiota and their metabolites alterations during and after COVID-19 infection and focus on potential therapeutic strategies targeting gut microbiota. Understanding the connections between intestinal microbiota and COVID-19 would provide new insights into COVID-19 management in the future.https://www.tandfonline.com/doi/10.1080/19490976.2023.2201157COVID-19gut microbiotamicrobiota-gut-lung axisprobioticsfecal microbiota transplantation |
| spellingShingle | Bingqian Zhou Xiaoqi Pang Jingyi Wu Tianyu Liu Bangmao Wang Hailong Cao Gut microbiota in COVID-19: new insights from inside Gut Microbes COVID-19 gut microbiota microbiota-gut-lung axis probiotics fecal microbiota transplantation |
| title | Gut microbiota in COVID-19: new insights from inside |
| title_full | Gut microbiota in COVID-19: new insights from inside |
| title_fullStr | Gut microbiota in COVID-19: new insights from inside |
| title_full_unstemmed | Gut microbiota in COVID-19: new insights from inside |
| title_short | Gut microbiota in COVID-19: new insights from inside |
| title_sort | gut microbiota in covid 19 new insights from inside |
| topic | COVID-19 gut microbiota microbiota-gut-lung axis probiotics fecal microbiota transplantation |
| url | https://www.tandfonline.com/doi/10.1080/19490976.2023.2201157 |
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