Enhanced fear limits behavioral flexibility in Shank2-deficient mice

Abstract Background A core symptom of autism spectrum disorder (ASD) is repetitive and restrictive patterns of behavior. Cognitive inflexibility has been proposed as a potential basis for these symptoms of ASD. More generally, behavioral inflexibility has been proposed to underlie repetitive and res...

Full description

Bibliographic Details
Main Authors: Miru Yun, Eunjoon Kim, Min Whan Jung
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Molecular Autism
Subjects:
Online Access:https://doi.org/10.1186/s13229-022-00518-1