Structural topological analysis of spike proteins of SARS-CoV-2 variants of concern highlight distinctive amino acid substitution patterns

Structural topological analysis of spike proteins of SARS-CoV-2 variants of concern highlight distinctive amino acid substitution patterns

Since the onset of pandemic in 2019, SARS-CoV-2 has diverged into numerous variants driven by antigenic and infectivity-oriented selection. Some variants have accumulated fitness-enhancing mutations, evaded immunity and spread despite global vaccination campaigns. The spike (S) glycoprotein of SARS-...

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Bibliographic Details
Main Authors: Filips Peisahovics, Mohammed A. Rohaim, Muhammad Munir
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:European Journal of Cell Biology
Subjects:
Viruses
Cell biology
Variants
Structural biology
Evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933522000784

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