Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model
Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are platelet concentrates which have been used to improve healing and regeneration of damaged tissues. The concentration of growth factors greatly influences the final outcome of the treatment. For studying the effects of PRP and PRF, an anim...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Czech Academy of Agricultural Sciences
2016-10-01
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| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-201610-0005_concentrations-of-growth-factors-in-platelet-rich-plasma-and-platelet-rich-fibrin-in-a-rabbit-model.php |
| _version_ | 1797897495418765312 |
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| author | J. Vokurka E. Gopfert M. Blahutkova E. Buchalova M. Faldyna |
| author_facet | J. Vokurka E. Gopfert M. Blahutkova E. Buchalova M. Faldyna |
| author_sort | J. Vokurka |
| collection | DOAJ |
| description | Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are platelet concentrates which have been used to improve healing and regeneration of damaged tissues. The concentration of growth factors greatly influences the final outcome of the treatment. For studying the effects of PRP and PRF, an animal model is required. The New Zealand White rabbit appears to be a good candidate for studying the features of these blood derivatives. This article presents for the first time the various preparation methods of blood derivatives with regard to concentration of growth factors - insulin-like growth factor, transforming growth factor and vascular endothelial growth factor. There was no statistically significant difference among the methods in the case of the first two factors. In the case of vascular endothelial growth factor, the lowest amount was detected in PRF. This study, even though performed on a limited number of animals, reports novel characterisation of the rabbit as an animal model for in vivo studies of the action of these blood derivatives. |
| first_indexed | 2024-04-10T07:59:22Z |
| format | Article |
| id | doaj.art-230760601e4c4cacb471d13bfc19b3a7 |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T07:59:22Z |
| publishDate | 2016-10-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-230760601e4c4cacb471d13bfc19b3a72023-02-23T03:50:32ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922016-10-01611056757010.17221/24/2016-VETMEDvet-201610-0005Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit modelJ. Vokurka0E. Gopfert1M. Blahutkova2E. Buchalova3M. Faldyna4Clinic of Dentistry, St. Anne's Faculty Hospital, Brno, Czech RepublicVeterinary Research Institute, Brno, Czech RepublicVeterinary Research Institute, Brno, Czech RepublicClinic of Dentistry, St. Anne's Faculty Hospital, Brno, Czech RepublicVeterinary Research Institute, Brno, Czech RepublicPlatelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are platelet concentrates which have been used to improve healing and regeneration of damaged tissues. The concentration of growth factors greatly influences the final outcome of the treatment. For studying the effects of PRP and PRF, an animal model is required. The New Zealand White rabbit appears to be a good candidate for studying the features of these blood derivatives. This article presents for the first time the various preparation methods of blood derivatives with regard to concentration of growth factors - insulin-like growth factor, transforming growth factor and vascular endothelial growth factor. There was no statistically significant difference among the methods in the case of the first two factors. In the case of vascular endothelial growth factor, the lowest amount was detected in PRF. This study, even though performed on a limited number of animals, reports novel characterisation of the rabbit as an animal model for in vivo studies of the action of these blood derivatives.https://vetmed.agriculturejournals.cz/artkey/vet-201610-0005_concentrations-of-growth-factors-in-platelet-rich-plasma-and-platelet-rich-fibrin-in-a-rabbit-model.phpblood derivatethrombocyteprpprfhealinganimal model |
| spellingShingle | J. Vokurka E. Gopfert M. Blahutkova E. Buchalova M. Faldyna Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model Veterinární Medicína blood derivate thrombocyte prp prf healing animal model |
| title | Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model |
| title_full | Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model |
| title_fullStr | Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model |
| title_full_unstemmed | Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model |
| title_short | Concentrations of growth factors in platelet-rich plasma and platelet-rich fibrin in a rabbit model |
| title_sort | concentrations of growth factors in platelet rich plasma and platelet rich fibrin in a rabbit model |
| topic | blood derivate thrombocyte prp prf healing animal model |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-201610-0005_concentrations-of-growth-factors-in-platelet-rich-plasma-and-platelet-rich-fibrin-in-a-rabbit-model.php |
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