Long-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction
Introduction. Myocardial infarction is the most common cause of death in patients with diabetes, and several studies have shown that people with diabetes have twice the risk of dying from a heart attack compared to non diabetics. Objective. The aim of this study was to determine the mortality of pat...
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| Format: | Article |
| Language: | English |
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Serbian Medical Society, Belgrade
2014-01-01
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| Series: | Opšta Medicina |
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| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/0354-7132/2014/0354-71321402042M.pdf |
| _version_ | 1818733933766901760 |
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| author | Miljković Dušan |
| author_facet | Miljković Dušan |
| author_sort | Miljković Dušan |
| collection | DOAJ |
| description | Introduction. Myocardial infarction is the most common cause of death in patients with diabetes, and several studies have shown that people with diabetes have twice the risk of dying from a heart attack compared to non diabetics. Objective. The aim of this study was to determine the mortality of patients that have survived acute myocardial infarction, in population of patients with diabetes mellitus and without diabetes. Method. The study included 135 patients recovered from myocardial infarction, of whom 51 (37.8%) had type 2 diabetes mellitus, and 84 (62.2%) were without diabetes, mean age 55,4±9,6 years. All patients underwent a complete cardiac and hemodynamic testing, cardiac catheterization with selective coronary angiography, and in most patients the aortocoronary bypass revascularization or percutaneous coronary intervention. Start of follow-up was the date of acute myocardial infarction. The study included only patients who survived at least one month after acute myocardial infarction. All patients with diabetes and without diabetes were monitored for an average of 84 months, i.e. 7 years. Results. The average age of patients with diabetes and myocardial infarction was 57.1±8.7 years, and of patients with myocardial infarction without diabetes 54.5 ± 9.6 years (t=1.62; p>0.05). Among patients with diabetes 14 (27.5%) were women and 37 (72.5%) were men, and in non-diabetics 15 (17.9%) were women and 69 (82.1%) were men (χ2=1.66; p>0.05). In the follow-up period died 15 (29.4%) patients with diabetes, and 7 (8.3%) patients without diabetes. Mortality in patients with diabetes and myocardial infarction was significantly higher than the mortality of patients with myocardial infarction without diabetes (χ2=11.2; p<0.01). The average annual mortality of patients with diabetes was 4.2%, and of patients without diabetes 1.2%, or 3.5 times les. Mortality in diabetic women was 2 (14.3%) and in diabetic men 13 (35,1%) (χ2=3.15; p>0.05). In the group of 27 patients who were treated with insulin, died five (18.5%) and in the group of 24 patients on oral therapy died 10 (41.7%). There was no significant difference in mortality in patients with diabetes treated with insulin or oral antidiabetics (χ2=3.61; p>0.05). |
| first_indexed | 2024-12-17T23:57:20Z |
| format | Article |
| id | doaj.art-230c30b81bc0442c80032814aa21f18d |
| institution | Directory Open Access Journal |
| issn | 0354-7132 2217-3994 |
| language | English |
| last_indexed | 2024-12-17T23:57:20Z |
| publishDate | 2014-01-01 |
| publisher | Serbian Medical Society, Belgrade |
| record_format | Article |
| series | Opšta Medicina |
| spelling | doaj.art-230c30b81bc0442c80032814aa21f18d2022-12-21T21:28:01ZengSerbian Medical Society, BelgradeOpšta Medicina0354-71322217-39942014-01-01201-2425110.5937/opmed1402042M0354-71321402042MLong-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarctionMiljković Dušan0Dom zdravlja, Varvarin, SerbiaIntroduction. Myocardial infarction is the most common cause of death in patients with diabetes, and several studies have shown that people with diabetes have twice the risk of dying from a heart attack compared to non diabetics. Objective. The aim of this study was to determine the mortality of patients that have survived acute myocardial infarction, in population of patients with diabetes mellitus and without diabetes. Method. The study included 135 patients recovered from myocardial infarction, of whom 51 (37.8%) had type 2 diabetes mellitus, and 84 (62.2%) were without diabetes, mean age 55,4±9,6 years. All patients underwent a complete cardiac and hemodynamic testing, cardiac catheterization with selective coronary angiography, and in most patients the aortocoronary bypass revascularization or percutaneous coronary intervention. Start of follow-up was the date of acute myocardial infarction. The study included only patients who survived at least one month after acute myocardial infarction. All patients with diabetes and without diabetes were monitored for an average of 84 months, i.e. 7 years. Results. The average age of patients with diabetes and myocardial infarction was 57.1±8.7 years, and of patients with myocardial infarction without diabetes 54.5 ± 9.6 years (t=1.62; p>0.05). Among patients with diabetes 14 (27.5%) were women and 37 (72.5%) were men, and in non-diabetics 15 (17.9%) were women and 69 (82.1%) were men (χ2=1.66; p>0.05). In the follow-up period died 15 (29.4%) patients with diabetes, and 7 (8.3%) patients without diabetes. Mortality in patients with diabetes and myocardial infarction was significantly higher than the mortality of patients with myocardial infarction without diabetes (χ2=11.2; p<0.01). The average annual mortality of patients with diabetes was 4.2%, and of patients without diabetes 1.2%, or 3.5 times les. Mortality in diabetic women was 2 (14.3%) and in diabetic men 13 (35,1%) (χ2=3.15; p>0.05). In the group of 27 patients who were treated with insulin, died five (18.5%) and in the group of 24 patients on oral therapy died 10 (41.7%). There was no significant difference in mortality in patients with diabetes treated with insulin or oral antidiabetics (χ2=3.61; p>0.05).https://scindeks-clanci.ceon.rs/data/pdf/0354-7132/2014/0354-71321402042M.pdfdiabetes mellitusmyocardial infarctionmortality |
| spellingShingle | Miljković Dušan Long-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction Opšta Medicina diabetes mellitus myocardial infarction mortality |
| title | Long-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction |
| title_full | Long-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction |
| title_fullStr | Long-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction |
| title_full_unstemmed | Long-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction |
| title_short | Long-term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction |
| title_sort | long term mortality in patients with diabetes mellitus type 2 after acute myocardial infarction |
| topic | diabetes mellitus myocardial infarction mortality |
| url | https://scindeks-clanci.ceon.rs/data/pdf/0354-7132/2014/0354-71321402042M.pdf |
| work_keys_str_mv | AT miljkovicdusan longtermmortalityinpatientswithdiabetesmellitustype2afteracutemyocardialinfarction |