Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022)
Influenza and Coronavirus Disease 2019 (COVID-19) vaccination are recommended in both solid organ transplant (SOT) candidates and recipients. In Puglia, Southern Italy, an active vaccination offer program has been activated targeting these patients. This study aims at investigating vaccination cover...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | http://dx.doi.org/10.1080/21645515.2023.2266932 |
| _version_ | 1827767349819736064 |
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| author | Pasquale Stefanizzi Francesco Paolo Bianchi Lorenza Moscara Andrea Martinelli Antonio Di Lorenzo Loreto Gesualdo Simona Simone Maria Rendina Silvio Tafuri |
| author_facet | Pasquale Stefanizzi Francesco Paolo Bianchi Lorenza Moscara Andrea Martinelli Antonio Di Lorenzo Loreto Gesualdo Simona Simone Maria Rendina Silvio Tafuri |
| author_sort | Pasquale Stefanizzi |
| collection | DOAJ |
| description | Influenza and Coronavirus Disease 2019 (COVID-19) vaccination are recommended in both solid organ transplant (SOT) candidates and recipients. In Puglia, Southern Italy, an active vaccination offer program has been activated targeting these patients. This study aims at investigating vaccination coverage (VC) for both vaccines in a SOT patients’ cohort, as well as at identifying the vaccination compliance determinant. This is a retrospective, population-based study. The study population consists of the SOT patients who accessed Bari’s “Policlinico” General Hospital during 2017–2022. Patients were contacted and, after providing their consent, asked their immunization status regarding influenza and COVID-19 and whether they had already undergone transplant or were waiting to do so. Regression models were fitted to investigate the determinants of VCs for influenza vaccination (2021/22 and 2022/23 seasons) and for COVID-19 vaccination (three-dose base cycle, first and second booster doses). Three-hundred and ten SOT patients were identified; 85.2% (264/310) had already undergone SOT. VCs were suboptimal, especially for constant yearly influenza vaccination (17.7%) and COVID-19 vaccination’s second booster (1.94%). Logistic regression highlighted that influenza VCs are higher for SOT recipients than SOT candidates, as well as for older patients, although when considering both vaccination seasons only age significantly impact the vaccination uptake. Older age was the only influential variable for COVID-19 VC. VCs for SOT patients seem to be unsatisfying. Stronger interventions are required. |
| first_indexed | 2024-03-11T11:57:31Z |
| format | Article |
| id | doaj.art-231058ca84cc44af80d38a810beb1271 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T11:57:31Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-231058ca84cc44af80d38a810beb12712023-11-08T11:55:20ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-12-0119310.1080/21645515.2023.22669322266932Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022)Pasquale Stefanizzi0Francesco Paolo Bianchi1Lorenza Moscara2Andrea Martinelli3Antonio Di Lorenzo4Loreto Gesualdo5Simona Simone6Maria Rendina7Silvio Tafuri8University of Bari Aldo MoroUniversity of Bari Aldo MoroUniversity of Bari Aldo MoroUniversity of Bari Aldo MoroUniversity of Bari Aldo MoroUniversity of Bari Aldo MoroUniversity of Bari Aldo MoroUniversity of BariUniversity of Bari Aldo MoroInfluenza and Coronavirus Disease 2019 (COVID-19) vaccination are recommended in both solid organ transplant (SOT) candidates and recipients. In Puglia, Southern Italy, an active vaccination offer program has been activated targeting these patients. This study aims at investigating vaccination coverage (VC) for both vaccines in a SOT patients’ cohort, as well as at identifying the vaccination compliance determinant. This is a retrospective, population-based study. The study population consists of the SOT patients who accessed Bari’s “Policlinico” General Hospital during 2017–2022. Patients were contacted and, after providing their consent, asked their immunization status regarding influenza and COVID-19 and whether they had already undergone transplant or were waiting to do so. Regression models were fitted to investigate the determinants of VCs for influenza vaccination (2021/22 and 2022/23 seasons) and for COVID-19 vaccination (three-dose base cycle, first and second booster doses). Three-hundred and ten SOT patients were identified; 85.2% (264/310) had already undergone SOT. VCs were suboptimal, especially for constant yearly influenza vaccination (17.7%) and COVID-19 vaccination’s second booster (1.94%). Logistic regression highlighted that influenza VCs are higher for SOT recipients than SOT candidates, as well as for older patients, although when considering both vaccination seasons only age significantly impact the vaccination uptake. Older age was the only influential variable for COVID-19 VC. VCs for SOT patients seem to be unsatisfying. Stronger interventions are required.http://dx.doi.org/10.1080/21645515.2023.2266932hesitancyvaccination coveragesafetyhigh risk group |
| spellingShingle | Pasquale Stefanizzi Francesco Paolo Bianchi Lorenza Moscara Andrea Martinelli Antonio Di Lorenzo Loreto Gesualdo Simona Simone Maria Rendina Silvio Tafuri Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022) Human Vaccines & Immunotherapeutics hesitancy vaccination coverage safety high risk group |
| title | Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022) |
| title_full | Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022) |
| title_fullStr | Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022) |
| title_full_unstemmed | Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022) |
| title_short | Determinants of compliance to influenza and COVID-19 vaccination in a cohort of solid organ transplant patients in Puglia, Southern Italy (2017–2022) |
| title_sort | determinants of compliance to influenza and covid 19 vaccination in a cohort of solid organ transplant patients in puglia southern italy 2017 2022 |
| topic | hesitancy vaccination coverage safety high risk group |
| url | http://dx.doi.org/10.1080/21645515.2023.2266932 |
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